NBP2-45298-0.1mg

antibody from Novus Biologicals
Targeting: GNRHR GRHR, LHRHR
Provider product page for NBP2-45298-0.1mg
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-45298-0.1mg - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal GnRHR Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.
Reactivity
Human, Rat
Host
Mouse
Isotype
IgG
Vial size
0.1 mg
Concentration
0.2 mg/ml
Storage
Store at 4C.
GNRHR protein structure - NBP2-45298-0.1mg shown in red.