BS8286

antibody from Bioworld Technology, Inc
Targeting: GLP2R
Provider product page for BS8286
Western blot
Immunohistochemistry

Antibody data

Product number
BS8286 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GLP2R polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GLP2R.
Description
Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both Glucagon and GLP-1 function through their specific binding to the Glucagon Receptor or GLP-1R, respectively. The Glucagon Receptor is expressed in liver, kidney and adipose tissue. The GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes. Glucagon-like peptide 2 receptor, also designated GLP-2 receptor or glp-2r, acts as a receptor for Glucagon-like peptide 2 (GLP-2). GLP-2 is a nutrient-responsive hormone that has various functions in the gastrointestinal tract. The activity of GLP-2R, which is a multi-pass membrane protein, is mediated by G-proteins which activate adenylyl cyclase.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GLP2R protein structure - BS8286 shown in red.