CABT-L539

antibody from Creative Diagnostics

Targeting: ATF4 CREB-2, TAXREB67, TXREB

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-L539

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human ATF4 polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Reactivity

Human, Mouse, Rat, Porcine

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Concentration

43 Ã×g / 150 Ã×l

Storage

Store at -20°C. Aliquoting is unnecessary for -20°C storage.