CABT-L623

antibody from Creative Diagnostics

Targeting: IRF3

No application information provided.

Antibody Data

Product number

CABT-L623

Provider

Creative Diagnostics

Product name

Rabbit Anti-Calmodulin monoclonal antibody, clone TK27-10

Antibody type

Monoclonal

Description

The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. CaM directly modulates the activity of protein kinases and phosphatases, ion channels and nitric oxide synthetases. It is generally involved in such diverse processes as cell proliferation, endocytosis, cellular adhesion, protein turn over and smooth muscle contraction. CaM (calmodulin) is an acidic protein, 148 amino acids in length, with four helix-loop-helix calcium binding domains. In humans, 3 distinct genes have been identified (CALM1, CALM2 and CALM3)