BS6169

antibody from Bioworld Technology, Inc
Targeting: MCM7 CDC47, MCM2, PPP1R104
Provider product page for BS6169
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6169 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MCM7 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MCM7.
Description
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MCM7 protein structure - BS6169 shown in red.