CABT-B1601

antibody from Creative Diagnostics

Targeting: TRAF3 CAP-1, CD40bp, CRAF1, LAP1, RNF118

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B1601

Provider

Creative Diagnostics

Product name

Anti-TRAF3 polyclonal antibody

Antibody type

Polyclonal

Description

TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote Lys-63-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both Lys-48-linked and Lys-63-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _g

Concentration

Please refer to lot specific datasheet.

Storage

Stable for 1 year at 2-8°C from date of receipt.