Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-7502 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-GRP94 Antibody
- Antibody type
- Polyclonal
- Description
- GRP94 (94 kDa glucose-regulated protein) is a 92 kDa protein belonging to the heat shock protein 90 family of molecular chaperones. GRP94 is mainly involved in protein folding, stabilization and refolding of denatured proteins. GRP94 has also been reported to trigger CTL expansion and maturation of human monocytes-derived dendritic cells (MDDC). GRP94 is also involved in inducing tumor and is used as a potential marker in breast cancer. GRP94 is localized in endoplasmic reticulum lumen and melanosome. GRP94 is highly expressed in melanoma or liver metastases of colon carcinoma cells and human gastric carcinoma.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant GRP94
protein (amino acids 420-700) was u
sed as the immunogen for this antib
ody.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of GRP94. Anti-GRP94 antibody (11-7502) was used at 2 µg/ml on 1) HepG2, 2) Raji lysates.