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Western blot
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- ADI-SPA-851-D - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-SPA-851-D, RRID:AB_2039136
- Product name
- Grp94 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Protein A affinity purified.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Vial size
- 50 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Characterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface.
The molecular chaperone gp96/GRP94 interacts with Toll-like receptors and integrins via its C-terminal hydrophobic domain.
Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages.
Human U251MG glioma cells expressing the membrane form of macrophage colony-stimulating factor (mM-CSF) are killed by human monocytes in vitro and are rejected within immunodeficient mice via paraptosis that is associated with increased expression of three different heat shock proteins.
Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice.
Induction of GRP78 by ischemic preconditioning reduces endoplasmic reticulum stress and prevents delayed neuronal cell death.
Overexpression of glucose-regulated protein 94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans.
Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2.
The C-terminal domain of human grp94 protects the catalytic subunit of protein kinase CK2 (CK2alpha) against thermal aggregation. Role of disulfide bonds.
A novel human cytomegalovirus glycoprotein, gpUS9, which promotes cell-to-cell spread in polarized epithelial cells, colocalizes with the cytoskeletal proteins E-cadherin and F-actin.
Tsai YL, Zhang Y, Tseng CC, Stanciauskas R, Pinaud F, Lee AS
The Journal of biological chemistry 2015 Mar 27;290(13):8049-64
The Journal of biological chemistry 2015 Mar 27;290(13):8049-64
The molecular chaperone gp96/GRP94 interacts with Toll-like receptors and integrins via its C-terminal hydrophobic domain.
Wu S, Hong F, Gewirth D, Guo B, Liu B, Li Z
The Journal of biological chemistry 2012 Feb 24;287(9):6735-42
The Journal of biological chemistry 2012 Feb 24;287(9):6735-42
Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages.
Yang Y, Liu B, Dai J, Srivastava PK, Zammit DJ, Lefrançois L, Li Z
Immunity 2007 Feb;26(2):215-26
Immunity 2007 Feb;26(2):215-26
Human U251MG glioma cells expressing the membrane form of macrophage colony-stimulating factor (mM-CSF) are killed by human monocytes in vitro and are rejected within immunodeficient mice via paraptosis that is associated with increased expression of three different heat shock proteins.
Jadus MR, Chen Y, Boldaji MT, Delgado C, Sanchez R, Douglass T, Al-Atar U, Schulz W, Lloyd C, Wepsic HT
Cancer gene therapy 2003 May;10(5):411-20
Cancer gene therapy 2003 May;10(5):411-20
Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice.
Shie FS, LeBoeuf RC, Jin LW
Neuroreport 2003 Jan 20;14(1):123-9
Neuroreport 2003 Jan 20;14(1):123-9
Induction of GRP78 by ischemic preconditioning reduces endoplasmic reticulum stress and prevents delayed neuronal cell death.
Hayashi T, Saito A, Okuno S, Ferrand-Drake M, Chan PH
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003 Aug;23(8):949-61
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003 Aug;23(8):949-61
Overexpression of glucose-regulated protein 94 (Grp94) in esophageal adenocarcinomas of a rat surgical model and humans.
Chen X, Ding Y, Liu CG, Mikhail S, Yang CS
Carcinogenesis 2002 Jan;23(1):123-30
Carcinogenesis 2002 Jan;23(1):123-30
Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2.
Guo Z, Lee J, Lane M, Mattson M
Journal of neurochemistry 2001 Oct;79(2):361-70
Journal of neurochemistry 2001 Oct;79(2):361-70
The C-terminal domain of human grp94 protects the catalytic subunit of protein kinase CK2 (CK2alpha) against thermal aggregation. Role of disulfide bonds.
Roher N, Miró F, Boldyreff B, Llorens F, Plana M, Issinger OG, Itarte E
European journal of biochemistry / FEBS 2001 Jan;268(2):429-36
European journal of biochemistry / FEBS 2001 Jan;268(2):429-36
A novel human cytomegalovirus glycoprotein, gpUS9, which promotes cell-to-cell spread in polarized epithelial cells, colocalizes with the cytoskeletal proteins E-cadherin and F-actin.
Maidji E, Tugizov S, Abenes G, Jones T, Pereira L
Journal of virology 1998 Jul;72(7):5717-27
Journal of virology 1998 Jul;72(7):5717-27
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Supportive validation
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- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of human small intestine tissue stained with Grp94, pAb at 10µg/ml.
