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LearnNBP1-05987
antibody from Novus Biologicals
Targeting: ZEB1
AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a
Western blot
Immunocytochemistry Immunoprecipitation Immunohistochemistry Gel shift Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [57]
- Comments [0]
- Validations
- Western blot [4]
- Immunoprecipitation [1]
- Immunohistochemistry [6]
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- Product number
- NBP1-05987 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-05987, RRID:AB_1556166
- Product name
- Rabbit Polyclonal ZEB1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references ZEB1 modulates endometrial receptivity through epithelial-mesenchymal transition in endometrial epithelial cells in vitro.
Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity.
The diagnostic utility of zinc E-box 1 (ZEB1) transcription factor for identification of pulmonary sarcomatoid carcinoma in cytologic and surgical specimens.
OVOL2-Mediated ZEB1 Downregulation May Prevent Promotion of Actinic Keratosis to Cutaneous Squamous Cell Carcinoma.
ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas.
KRAS Activation in Gastric Adenocarcinoma Stimulates Epithelial-to-Mesenchymal Transition to Cancer Stem-Like Cells and Promotes Metastasis.
Nicotinamide N‑methyltransferase induces the proliferation and invasion of squamous cell carcinoma cells.
Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch.
Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI.
Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition.
Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors through TGFβ1.
Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas.
Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours.
Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.
High expression of ZEB1 in endometriosis and its role in 17β-estradiol-induced epithelial-mesenchymal transition.
Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells.
Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.
Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition.
Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells.
Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas.
KMT2C Mutations in Diffuse-Type Gastric Adenocarcinoma Promote Epithelial-to-Mesenchymal Transition.
Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade.
Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells.
ZEB1-regulated inflammatory phenotype in breast cancer cells.
The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent.
Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells.
Senescent tumor cells lead the collective invasion in thyroid cancer.
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers.
Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes.
Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma.
Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors.
Heterogeneous expression of zinc-finger E-box-binding homeobox 1 plays a pivotal role in metastasis via regulation of miR-200c in epithelial-mesenchymal transition.
Effects of Kras activation and Pten deletion alone or in combination on MUC1 biology and epithelial-to-mesenchymal transition in ovarian cancer.
Identification of blood vascular endothelial stem cells by the expression of protein C receptor.
Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth.
Sarcomatoid Urothelial Carcinoma of the Bladder: Analysis of 28 Cases With Emphasis on Clinicopathologic Features and Markers of Epithelial-to-Mesenchymal Transition.
Chemotherapy Resistance in Diffuse-Type Gastric Adenocarcinoma Is Mediated by RhoA Activation in Cancer Stem-Like Cells.
MiR-200c and miR-141 inhibit ZEB1 synergistically and suppress glioma cell growth and migration.
Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages.
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.
Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion.
ZEB1 promotes epithelial-mesenchymal transition in cervical cancer metastasis.
Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis.
δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells.
Changes in microRNA expression during disease progression in patients with chronic viral hepatitis.
Decreased expression of miR216a contributes to non-small-cell lung cancer progression.
Deregulation of the cell polarity protein Lethal giant larvae 2 (Lgl2) correlates with gastric cancer progression.
MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition.
Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states.
Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy.
A quantitative method to identify microRNAs targeting a messenger RNA using a 3'UTR RNA affinity technique.
miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma.
Combination of epithelial-mesenchymal transition and cancer stem cell-like phenotypes has independent prognostic value in gastric cancer.
miR-200b regulates cell migration via Zeb family during mouse palate development.
Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications.
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.
Ran J, Yang HH, Huang HP, Huang HL, Xu Z, Zhang W, Wang ZX
Biochemical and biophysical research communications 2020 May 7;525(3):699-705
Biochemical and biophysical research communications 2020 May 7;525(3):699-705
Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity.
Horn LA, Riskin J, Hempel HA, Fousek K, Lind H, Hamilton DH, McCampbell KK, Maeda DY, Zebala JA, Su Z, Schlom J, Palena C
Journal for immunotherapy of cancer 2020 Mar;8(1)
Journal for immunotherapy of cancer 2020 Mar;8(1)
The diagnostic utility of zinc E-box 1 (ZEB1) transcription factor for identification of pulmonary sarcomatoid carcinoma in cytologic and surgical specimens.
Viswanathan K, Siddiqui MT, Borczuk AC
Journal of the American Society of Cytopathology 2020 Jan - Feb;9(1):55-61
Journal of the American Society of Cytopathology 2020 Jan - Feb;9(1):55-61
OVOL2-Mediated ZEB1 Downregulation May Prevent Promotion of Actinic Keratosis to Cutaneous Squamous Cell Carcinoma.
Murata M, Ito T, Tanaka Y, Yamamura K, Furue K, Furue M
Journal of clinical medicine 2020 Feb 25;9(3)
Journal of clinical medicine 2020 Feb 25;9(3)
ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas.
Huang C, Yoon C, Zhou XH, Zhou YC, Zhou WW, Liu H, Yang X, Lu J, Lee SY, Huang K
Cell death & disease 2020 Apr 23;11(4):266
Cell death & disease 2020 Apr 23;11(4):266
KRAS Activation in Gastric Adenocarcinoma Stimulates Epithelial-to-Mesenchymal Transition to Cancer Stem-Like Cells and Promotes Metastasis.
Yoon C, Till J, Cho SJ, Chang KK, Lin JX, Huang CM, Ryeom S, Yoon SS
Molecular cancer research : MCR 2019 Sep;17(9):1945-1957
Molecular cancer research : MCR 2019 Sep;17(9):1945-1957
Nicotinamide N‑methyltransferase induces the proliferation and invasion of squamous cell carcinoma cells.
Hah YS, Cho HY, Jo SY, Park YS, Heo EP, Yoon TJ
Oncology reports 2019 Nov;42(5):1805-1814
Oncology reports 2019 Nov;42(5):1805-1814
Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch.
Miro C, Di Cicco E, Ambrosio R, Mancino G, Di Girolamo D, Cicatiello AG, Sagliocchi S, Nappi A, De Stefano MA, Luongo C, Antonini D, Visconte F, Varricchio S, Ilardi G, Del Vecchio L, Staibano S, Boelen A, Blanpain C, Missero C, Salvatore D, Dentice M
Nature communications 2019 Nov 27;10(1):5410
Nature communications 2019 Nov 27;10(1):5410
Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI.
Weng CH, Chen LY, Lin YC, Shih JY, Lin YC, Tseng RY, Chiu AC, Yeh YH, Liu C, Lin YT, Fang JM, Chen CC
Oncogene 2019 Jan;38(4):455-468
Oncogene 2019 Jan;38(4):455-468
Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition.
Katsuno Y, Meyer DS, Zhang Z, Shokat KM, Akhurst RJ, Miyazono K, Derynck R
Science signaling 2019 Feb 26;12(570)
Science signaling 2019 Feb 26;12(570)
Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors through TGFβ1.
Sippel TR, Johnson AM, Li HY, Hanson D, Nguyen TT, Bullock BL, Poczobutt JM, Kwak JW, Kleczko EK, Weiser-Evans MC, Nemenoff RA
Molecular cancer research : MCR 2019 Aug;17(8):1748-1758
Molecular cancer research : MCR 2019 Aug;17(8):1748-1758
Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas.
Fujiwara S, Saiki Y, Ishizawa K, Fukushige S, Yamanaka M, Sato M, Ishida M, Motoi F, Unno M, Horii A
Cancer medicine 2019 Apr;8(4):1671-1678
Cancer medicine 2019 Apr;8(4):1671-1678
Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours.
Ordonez LD, Hay T, McEwen R, Polanska UM, Hughes A, Delpuech O, Cadogan E, Powell S, Dry J, Tornillo G, Silcock L, Leo E, O'Connor MJ, Clarke AR, Smalley MJ
Oncotarget 2019 Apr 5;10(27):2586-2606
Oncotarget 2019 Apr 5;10(27):2586-2606
Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.
Rios AC, Capaldo BD, Vaillant F, Pal B, van Ineveld R, Dawson CA, Chen Y, Nolan E, Fu NY, 3DTCLSM Group., Jackling FC, Devi S, Clouston D, Whitehead L, Smyth GK, Mueller SN, Lindeman GJ, Visvader JE
Cancer cell 2019 Apr 15;35(4):618-632.e6
Cancer cell 2019 Apr 15;35(4):618-632.e6
High expression of ZEB1 in endometriosis and its role in 17β-estradiol-induced epithelial-mesenchymal transition.
Wu RF, Chen ZX, Zhou WD, Li YZ, Huang ZX, Lin DC, Ren LL, Chen QX, Chen QH
International journal of clinical and experimental pathology 2018;11(10):4744-4758
International journal of clinical and experimental pathology 2018;11(10):4744-4758
Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells.
Maturi V, Enroth S, Heldin CH, Moustakas A
Journal of cellular physiology 2018 Oct;233(10):7113-7127
Journal of cellular physiology 2018 Oct;233(10):7113-7127
Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.
Chen Y, LeBleu VS, Carstens JL, Sugimoto H, Zheng X, Malasi S, Saur D, Kalluri R
EMBO molecular medicine 2018 Oct;10(10)
EMBO molecular medicine 2018 Oct;10(10)
Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition.
Jia D, Augert A, Kim DW, Eastwood E, Wu N, Ibrahim AH, Kim KB, Dunn CT, Pillai SPS, Gazdar AF, Bolouri H, Park KS, MacPherson D
Cancer discovery 2018 Nov;8(11):1422-1437
Cancer discovery 2018 Nov;8(11):1422-1437
Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells.
Maturi V, Morén A, Enroth S, Heldin CH, Moustakas A
Molecular oncology 2018 Jun;12(7):1153-1174
Molecular oncology 2018 Jun;12(7):1153-1174
Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas.
Chang KK, Yoon C, Yi BC, Tap WD, Simon MC, Yoon SS
Oncogenesis 2018 Jun 19;7(6):47
Oncogenesis 2018 Jun 19;7(6):47
KMT2C Mutations in Diffuse-Type Gastric Adenocarcinoma Promote Epithelial-to-Mesenchymal Transition.
Cho SJ, Yoon C, Lee JH, Chang KK, Lin JX, Kim YH, Kook MC, Aksoy BA, Park DJ, Ashktorab H, Smoot DT, Schultz N, Yoon SS
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Dec 15;24(24):6556-6569
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Dec 15;24(24):6556-6569
Expression of ZEBs in gliomas is associated with invasive properties and histopathological grade.
Suzuki K, Kawataki T, Endo K, Miyazawa K, Kinouchi H, Saitoh M
Oncology letters 2018 Aug;16(2):1758-1764
Oncology letters 2018 Aug;16(2):1758-1764
Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells.
Knaack H, Lenk L, Philipp LM, Miarka L, Rahn S, Viol F, Hauser C, Egberts JH, Gundlach JP, Will O, Tiwari S, Mikulits W, Schumacher U, Hengstler JG, Sebens S
Oncotarget 2018 Aug 3;9(60):31771-31786
Oncotarget 2018 Aug 3;9(60):31771-31786
ZEB1-regulated inflammatory phenotype in breast cancer cells.
Katsura A, Tamura Y, Hokari S, Harada M, Morikawa M, Sakurai T, Takahashi K, Mizutani A, Nishida J, Yokoyama Y, Morishita Y, Murakami T, Ehata S, Miyazono K, Koinuma D
Molecular oncology 2017 Sep;11(9):1241-1262
Molecular oncology 2017 Sep;11(9):1241-1262
The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent.
Acharya KD, Nettles SA, Sellers KJ, Im DD, Harling M, Pattanayak C, Vardar-Ulu D, Lichti CF, Huang S, Edwards DP, Srivastava DP, Denner L, Tetel MJ
eNeuro 2017 Sep-Oct;4(5)
eNeuro 2017 Sep-Oct;4(5)
Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells.
Sinh ND, Endo K, Miyazawa K, Saitoh M
Cancer science 2017 May;108(5):952-960
Cancer science 2017 May;108(5):952-960
Senescent tumor cells lead the collective invasion in thyroid cancer.
Kim YH, Choi YW, Lee J, Soh EY, Kim JH, Park TJ
Nature communications 2017 May 10;8:15208
Nature communications 2017 May 10;8:15208
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers.
Wang Y, Xu X, Yu S, Jeong KJ, Zhou Z, Han L, Tsang YH, Li J, Chen H, Mangala LS, Yuan Y, Eterovic AK, Lu Y, Sood AK, Scott KL, Mills GB, Liang H
Genome research 2017 Jul;27(7):1112-1125
Genome research 2017 Jul;27(7):1112-1125
Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes.
Liang X, Yuan X, Yu J, Wu Y, Li K, Sun C, Li S, Shen L, Kong F, Jia J, Björkholm M, Xu D
EBioMedicine 2017 Jul;21:104-116
EBioMedicine 2017 Jul;21:104-116
Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma.
Yoon C, Cho SJ, Chang KK, Park DJ, Ryeom SW, Yoon SS
Molecular cancer research : MCR 2017 Aug;15(8):1106-1116
Molecular cancer research : MCR 2017 Aug;15(8):1106-1116
Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors.
Lutz G, Jurak I, Kim ET, Kim JY, Hackenberg M, Leader A, Stoller ML, Fekete DM, Weitzman MD, Coen DM, Wilson AC
Viruses 2017 Aug 7;9(8)
Viruses 2017 Aug 7;9(8)
Heterogeneous expression of zinc-finger E-box-binding homeobox 1 plays a pivotal role in metastasis via regulation of miR-200c in epithelial-mesenchymal transition.
Muto Y, Suzuki K, Kato T, Tsujinaka S, Ichida K, Takayama Y, Fukui T, Kakizawa N, Watanabe F, Saito M, Futsuhara K, Noda H, Miyakura Y, Konishi F, Rikiyama T
International journal of oncology 2016 Sep;49(3):1057-67
International journal of oncology 2016 Sep;49(3):1057-67
Effects of Kras activation and Pten deletion alone or in combination on MUC1 biology and epithelial-to-mesenchymal transition in ovarian cancer.
Zhang L, Ma T, Brozick J, Babalola K, Budiu R, Tseng G, Vlad AM
Oncogene 2016 Sep 22;35(38):5010-20
Oncogene 2016 Sep 22;35(38):5010-20
Identification of blood vascular endothelial stem cells by the expression of protein C receptor.
Yu QC, Song W, Wang D, Zeng YA
Cell research 2016 Oct;26(10):1079-1098
Cell research 2016 Oct;26(10):1079-1098
Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth.
Werden SJ, Sphyris N, Sarkar TR, Paranjape AN, LaBaff AM, Taube JH, Hollier BG, Ramirez-Peña EQ, Soundararajan R, den Hollander P, Powell E, Echeverria GV, Miura N, Chang JT, Piwnica-Worms H, Rosen JM, Mani SA
Oncogene 2016 Nov 17;35(46):5977-5988
Oncogene 2016 Nov 17;35(46):5977-5988
Sarcomatoid Urothelial Carcinoma of the Bladder: Analysis of 28 Cases With Emphasis on Clinicopathologic Features and Markers of Epithelial-to-Mesenchymal Transition.
Sanfrancesco J, McKenney JK, Leivo MZ, Gupta S, Elson P, Hansel DE
Archives of pathology & laboratory medicine 2016 Jun;140(6):543-51
Archives of pathology & laboratory medicine 2016 Jun;140(6):543-51
Chemotherapy Resistance in Diffuse-Type Gastric Adenocarcinoma Is Mediated by RhoA Activation in Cancer Stem-Like Cells.
Yoon C, Cho SJ, Aksoy BA, Park DJ, Schultz N, Ryeom SW, Yoon SS
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Feb 15;22(4):971-83
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Feb 15;22(4):971-83
MiR-200c and miR-141 inhibit ZEB1 synergistically and suppress glioma cell growth and migration.
Guo E, Wang Z, Wang S
European review for medical and pharmacological sciences 2016 Aug;20(16):3385-91
European review for medical and pharmacological sciences 2016 Aug;20(16):3385-91
Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages.
Incio J, Suboj P, Chin SM, Vardam-Kaur T, Liu H, Hato T, Babykutty S, Chen I, Deshpande V, Jain RK, Fukumura D
PloS one 2015;10(12):e0141392
PloS one 2015;10(12):e0141392
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.
Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R
Nature 2015 Nov 26;527(7579):525-530
Nature 2015 Nov 26;527(7579):525-530
Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion.
Nolan KD, Franco OE, Hance MW, Hayward SW, Isaacs JS
The Journal of biological chemistry 2015 Mar 27;290(13):8271-82
The Journal of biological chemistry 2015 Mar 27;290(13):8271-82
ZEB1 promotes epithelial-mesenchymal transition in cervical cancer metastasis.
Ran J, Lin DL, Wu RF, Chen QH, Huang HP, Qiu NX, Quan S
Fertility and sterility 2015 Jun;103(6):1606-14.e1-2
Fertility and sterility 2015 Jun;103(6):1606-14.e1-2
Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis.
Liu YN, Yin J, Barrett B, Sheppard-Tillman H, Li D, Casey OM, Fang L, Hynes PG, Ameri AH, Kelly K
Molecular and cellular biology 2015 Jun 1;35(11):1940-51
Molecular and cellular biology 2015 Jun 1;35(11):1940-51
δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells.
Fukagawa A, Ishii H, Miyazawa K, Saitoh M
Cancer medicine 2015 Jan;4(1):125-35
Cancer medicine 2015 Jan;4(1):125-35
Changes in microRNA expression during disease progression in patients with chronic viral hepatitis.
Sinigaglia A, Lavezzo E, Trevisan M, Sanavia T, Di Camillo B, Peta E, Scarpa M, Castagliuolo I, Guido M, Sarcognato S, Cappellesso R, Fassina A, Cardin R, Farinati F, Palù G, Barzon L
Liver international : official journal of the International Association for the Study of the Liver 2015 Apr;35(4):1324-33
Liver international : official journal of the International Association for the Study of the Liver 2015 Apr;35(4):1324-33
Decreased expression of miR216a contributes to non-small-cell lung cancer progression.
Wang RT, Xu M, Xu CX, Song ZG, Jin H
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Sep 1;20(17):4705-16
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Sep 1;20(17):4705-16
Deregulation of the cell polarity protein Lethal giant larvae 2 (Lgl2) correlates with gastric cancer progression.
Nam KH, Kim MA, Choe G, Kim WH, Lee HS
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2014 Oct;17(4):610-20
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2014 Oct;17(4):610-20
MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition.
Rajabi H, Alam M, Takahashi H, Kharbanda A, Guha M, Ahmad R, Kufe D
Oncogene 2014 Mar 27;33(13):1680-9
Oncogene 2014 Mar 27;33(13):1680-9
Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states.
Yoshida T, Ozawa Y, Kimura T, Sato Y, Kuznetsov G, Xu S, Uesugi M, Agoulnik S, Taylor N, Funahashi Y, Matsui J
British journal of cancer 2014 Mar 18;110(6):1497-505
British journal of cancer 2014 Mar 18;110(6):1497-505
Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation.
Gore AJ, Deitz SL, Palam LR, Craven KE, Korc M
The Journal of clinical investigation 2014 Jan;124(1):338-52
The Journal of clinical investigation 2014 Jan;124(1):338-52
Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy.
Boyer JG, Murray LM, Scott K, De Repentigny Y, Renaud JM, Kothary R
Skeletal muscle 2013 Oct 11;3(1):24
Skeletal muscle 2013 Oct 11;3(1):24
A quantitative method to identify microRNAs targeting a messenger RNA using a 3'UTR RNA affinity technique.
Shi M, Han W, Spivack SD
Analytical biochemistry 2013 Dec 1;443(1):1-12
Analytical biochemistry 2013 Dec 1;443(1):1-12
miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma.
Ding W, Dang H, You H, Steinway S, Takahashi Y, Wang HG, Liao J, Stiles B, Albert R, Rountree CB
Oncogenesis 2012 Jun 11;1(6):e15
Oncogenesis 2012 Jun 11;1(6):e15
Combination of epithelial-mesenchymal transition and cancer stem cell-like phenotypes has independent prognostic value in gastric cancer.
Ryu HS, Park DJ, Kim HH, Kim WH, Lee HS
Human pathology 2012 Apr;43(4):520-8
Human pathology 2012 Apr;43(4):520-8
miR-200b regulates cell migration via Zeb family during mouse palate development.
Shin JO, Nakagawa E, Kim EJ, Cho KW, Lee JM, Cho SW, Jung HS
Histochemistry and cell biology 2012 Apr;137(4):459-70
Histochemistry and cell biology 2012 Apr;137(4):459-70
Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications.
Kizuka Y, Kitazume S, Yoshida M, Taniguchi N
The Journal of biological chemistry 2011 Sep 9;286(36):31875-84
The Journal of biological chemistry 2011 Sep 9;286(36):31875-84
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.
Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ
Molecular biology of the cell 2011 May 15;22(10):1686-98
Molecular biology of the cell 2011 May 15;22(10):1686-98
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ZEB1 Antibody [NBP1-05987] - Analysis of ZEB1 in transfected and native mouse cell lysate. Image courtesy of anonymous customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: ZEB1 Antibody [NBP1-05987] - Simple Western lane view shows a specific band for ZEB1 in 0.5 mg/ml of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ZEB1 Antibody [NBP1-05987] - Whole cell lysate from HeLa, 293T, and mouse NIH3T3 cells. ZEB1 was also immunoprecipitated by rabbit anti-ZEB1 antibody NBP1-05986, which recognizes an upstream epitope. Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells. Used at 0.04 ug/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ZEB1 Antibody [NBP1-05987] - Samples: Whole cell lysate (15 ug) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ZEB1 antibody (NBP1-05987) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunoprecipitation: ZEB1 Antibody [NBP1-05987] - Detection of human ZEB1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-ZEB1 antibody NBP1-05987 used for IP at 3 ug per reaction. ZEB1 was also immunoprecipitated by another rabbit anti-ZEB1 antibody. For blotting immunoprecipitated ZEB1, NBP1-05987 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Supportive validation
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- Novus Biologicals (provider)
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- Immunohistochemistry-Paraffin: ZEB1 Antibody [NBP1-05987] - Analysis of ZEB1 in human liver and spleen tissues. Image courtesy of anonymous customer review.
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- Novus Biologicals (provider)
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- Immunohistochemistry-Paraffin: ZEB1 Antibody [NBP1-05987] - FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ZEB1used at a dilution of 1:1000 (0.2ug/ml). Detection: DAB
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- Novus Biologicals (provider)
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- Immunohistochemistry-Paraffin: ZEB1 Antibody [NBP1-05987] - FFPE section of mouse colon carcinoma CT26. Antibody: Affinity purified rabbit anti-ZEB1 used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB
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- Novus Biologicals (provider)
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- Immunohistochemistry: ZEB1 Antibody [NBP1-05987] - Immunohistochemical staining results of EMT regulators in HG-PanIN: SNAIL, SLUG, TWIST1, and ZEB1. We categorized and defined three grades: grade 0,
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- Novus Biologicals (provider)
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- Immunohistochemistry-Paraffin: ZEB1 Antibody [NBP1-05987] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ZEB1 (NBP1-05987) used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ZEB1 Antibody [NBP1-05987] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ZEB1 (NBP1-05987) used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
