BS7684

antibody from Bioworld Technology, Inc
Targeting: BIN1 AMPH2, AMPHL, SH3P9
Provider product page for BS7684
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7684 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BIN1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human BIN1.
Description
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011]
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BIN1 protein structure - BS7684 shown in red.