V2721
antibody from NSJ Bioreagents
Targeting: MUC1
ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- V2721 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- MUC-1 Antibody
- Antibody type
- Monoclonal
- Antigen
- Human breast cancer cell line ZR-75 cells were used as the immunogen for the MUC-1 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- HMPV
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the MUC-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references MUC1 positive, Kras and Pten driven mouse gynecologic tumors replicate human tumors and vary in survival and nuclear grade based on anatomical location.
Induction of antigen-specific cytotoxic T lymphocytes by fusion cells generated from allogeneic plasmacytoid dendritic and tumor cells.
MUC1 and maltose‑binding protein recombinant fusion protein combined with Bacillus Calmette‑Guerin induces MUC1‑specific and nonspecific anti‑tumor immunity in mice.
Immunobiology of human mucin 1 in a preclinical ovarian tumor model.
Proteomic comparison of mcf-7 tumoursphere and monolayer cultures.
Three to Tango: MUC1 as a Ligand for Both E-Selectin and ICAM-1 in the Breast Cancer Metastatic Cascade.
Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.
Soluble MUC1 and serum MUC1-specific antibodies are potential prognostic biomarkers for platinum-resistant ovarian cancer.
Tirodkar TS, Budiu RA, Elishaev E, Zhang L, Mony JT, Brozick J, Edwards RP, Vlad AM
PloS one 2014;9(7):e102409
PloS one 2014;9(7):e102409
Induction of antigen-specific cytotoxic T lymphocytes by fusion cells generated from allogeneic plasmacytoid dendritic and tumor cells.
Koido S, Homma S, Kan S, Takakura K, Namiki Y, Kobayashi H, Ito Z, Uchiyama K, Kajihara M, Arihiro S, Arakawa H, Okamoto M, Ohkusa T, Gong J, Tajiri H
International journal of oncology 2014 Jul;45(1):470-8
International journal of oncology 2014 Jul;45(1):470-8
MUC1 and maltose‑binding protein recombinant fusion protein combined with Bacillus Calmette‑Guerin induces MUC1‑specific and nonspecific anti‑tumor immunity in mice.
Fang F, Ma J, Ni W, Wang F, Sun X, Li Y, Li Q, Xie F, Wang J, Zhai R, Liu Z, Gao S, Tai G
Molecular medicine reports 2014 Aug;10(2):1056-64
Molecular medicine reports 2014 Aug;10(2):1056-64
Immunobiology of human mucin 1 in a preclinical ovarian tumor model.
Budiu RA, Elishaev E, Brozick J, Lee M, Edwards RP, Kalinski P, Vlad AM
Oncogene 2013 Aug 8;32(32):3664-75
Oncogene 2013 Aug 8;32(32):3664-75
Proteomic comparison of mcf-7 tumoursphere and monolayer cultures.
Morrison BJ, Hastie ML, Grewal YS, Bruce ZC, Schmidt C, Reynolds BA, Gorman JJ, Lopez JA
PloS one 2012;7(12):e52692
PloS one 2012;7(12):e52692
Three to Tango: MUC1 as a Ligand for Both E-Selectin and ICAM-1 in the Breast Cancer Metastatic Cascade.
Geng Y, Yeh K, Takatani T, King MR
Frontiers in oncology 2012;2:76
Frontiers in oncology 2012;2:76
Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.
Weng D, Penzner JH, Song B, Koido S, Calderwood SK, Gong J
Breast cancer research : BCR 2012 Jan 25;14(1):R18
Breast cancer research : BCR 2012 Jan 25;14(1):R18
Soluble MUC1 and serum MUC1-specific antibodies are potential prognostic biomarkers for platinum-resistant ovarian cancer.
Budiu RA, Mantia-Smaldone G, Elishaev E, Chu T, Thaller J, McCabe K, Lenzner D, Edwards RP, Vlad AM
Cancer immunology, immunotherapy : CII 2011 Jul;60(7):975-84
Cancer immunology, immunotherapy : CII 2011 Jul;60(7):975-84
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of formalin-fixed, paraffin-embedded human ovarian carcinoma stained with MUC-1 antibody (HMPV).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free MUC-1 Antibody (clone HMPV). Confirmation of Integrity and Purity of the Antibody.