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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- 676902 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#676902, RRID:AB_2565723
- Product name
- Purified anti-IL-27 p28
- Antibody type
- Monoclonal
- Antigen
- Recombinant human IL-27.
- Description
- IL-27 is a heterodimeric cytokine that is composed of two subunits (p28 and EBI3). It plays a critical role in T-cell proliferation and differentiation. It also drives rapid clonal expansion of naive but not memory CD4 T cells. IL-27 is a potent inhibitor of Th17 cell development and IL-17 production. IL-27 subunit p28 alone is able to inhibit the production of IL-17 by CD4 and CD8 T cells. Furthermore, IL-27 plays an important role in antitumor and antiangiogenic activity through the increase in the production of antiangiogenic chemokines such as IP-10/CXCL10 and MIG/CXCL9.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- B0315A10
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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- BioLegend (provider)
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- Experimental details
- Western blot analysis of 50 ng recombinant human IL-27 (lane 1) and recombinant mouse IL-27 (lane 2) using anti-IL-27 P28 antibody (clone B0315A10) and HRP anti-mouse IgG antibody.
- Conjugate
- Unconjugated
