Tissue expression
Cell line expression
Protein structure
GPR150
G protein-coupled receptor 150PGR11
This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]
Top validated antibodies |
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OriGene | AP01258PU-N | Polyclonal |
WB
EL
ICC
IHC |
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GeneTex | GTX87397 | Polyclonal |
WB
EL
ICC
|
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St John's Laboratory | STJ93345 | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN1852896 | Polyclonal |
WB
EL
ICC
|
||
Cusabio Biotech Co., Ltd | CSB-PA008933 | Polyclonal |
WB
EL
ICC
|
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