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- References [5]
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- Product number
- ABIN953787 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Numb Homolog (NUMB) (AA 1-30), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 1-30, N-Term
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer.
Symmetric division and expression of its regulatory gene Numb in human cervical squamous carcinoma cells.
Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels.
Numb3 is an endocytosis adaptor for the inflammatory marker P-selectin.
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.
Rennstam K, McMichael N, Berglund P, Honeth G, Hegardt C, Rydén L, Luts L, Bendahl PO, Hedenfalk I
Breast cancer research and treatment 2010 Jul;122(2):315-24
Breast cancer research and treatment 2010 Jul;122(2):315-24
Symmetric division and expression of its regulatory gene Numb in human cervical squamous carcinoma cells.
Chen H, Chen X, Ye F, Lu W, Xie X
Pathobiology : journal of immunopathology, molecular and cellular biology 2009 May;76(3):149-54
Pathobiology : journal of immunopathology, molecular and cellular biology 2009 May;76(3):149-54
Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels.
Lu CB, Fu W, Xu X, Mattson MP
Neuroscience 2009 Jun 30;161(2):403-12
Neuroscience 2009 Jun 30;161(2):403-12
Numb3 is an endocytosis adaptor for the inflammatory marker P-selectin.
Schlüter T, Knauth P, Wald S, Boland S, Bohnensack R
Biochemical and biophysical research communications 2009 Feb 20;379(4):909-13
Biochemical and biophysical research communications 2009 Feb 20;379(4):909-13
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.
Kyriazis GA, Wei Z, Vandermey M, Jo DG, Xin O, Mattson MP, Chan SL
The Journal of biological chemistry 2008 Sep 12;283(37):25492-502
The Journal of biological chemistry 2008 Sep 12;283(37):25492-502
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
