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- Product number
- ABIN395505 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hephaestin (HEPH) (AA 315-425) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 315-425
- Isotype
- IgG
- Antibody clone number
- 2D3
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
Human hephaestin expression is not limited to enterocytes of the gastrointestinal tract but is also found in the antrum, the enteric nervous system, and pancreatic {beta}-cells.
Decreased hephaestin expression and activity leads to decreased iron efflux from differentiated Caco2 cells.
Neither human hephaestin nor ceruloplasmin forms a stable complex with transferrin.
Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells.
Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Dorak MT
Molecular human reproduction 2010 Oct;16(10):770-7
Molecular human reproduction 2010 Oct;16(10):770-7
Human hephaestin expression is not limited to enterocytes of the gastrointestinal tract but is also found in the antrum, the enteric nervous system, and pancreatic {beta}-cells.
Hudson DM, Curtis SB, Smith VC, Griffiths TA, Wong AY, Scudamore CH, Buchan AM, MacGillivray RT
American journal of physiology. Gastrointestinal and liver physiology 2010 Mar;298(3):G425-32
American journal of physiology. Gastrointestinal and liver physiology 2010 Mar;298(3):G425-32
Decreased hephaestin expression and activity leads to decreased iron efflux from differentiated Caco2 cells.
Chen H, Attieh ZK, Dang T, Huang G, van der Hee RM, Vulpe C
Journal of cellular biochemistry 2009 Jul 1;107(4):803-8
Journal of cellular biochemistry 2009 Jul 1;107(4):803-8
Neither human hephaestin nor ceruloplasmin forms a stable complex with transferrin.
Hudson DM, Krisinger MJ, Griffiths TA, Macgillivray RT
Journal of cellular biochemistry 2008 Apr 15;103(6):1849-55
Journal of cellular biochemistry 2008 Apr 15;103(6):1849-55
Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells.
Han O, Kim EY
Journal of cellular biochemistry 2007 Jul 1;101(4):1000-10
Journal of cellular biochemistry 2007 Jul 1;101(4):1000-10
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Supportive validation
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- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
