Explore
Validate
LearnNB100-879
antibody from Novus Biologicals
Targeting: ELMO2
CED-12, CED12, ELMO-2, FLJ11656, KIAA1834
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NB100-879 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-879, RRID:AB_2099164
- Product name
- Goat Polyclonal ELMO2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. NP_877496.1 and NP_573403.1 are varients that encode the same protein.
- Reactivity
- Human
- Host
- Goat
- Antigen sequence
C-PKEPSSYDFVYHYG- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.
Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.
ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions.
Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2.
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Hernández-Vásquez MN, Adame-García SR, Hamoud N, Chidiac R, Reyes-Cruz G, Gratton JP, Côté JF, Vázquez-Prado J
The Journal of biological chemistry 2017 Jul 21;292(29):12178-12191
The Journal of biological chemistry 2017 Jul 21;292(29):12178-12191
Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.
Abu-Thuraia A, Gauthier R, Chidiac R, Fukui Y, Screaton RA, Gratton JP, Côté JF
Molecular and cellular biology 2015 Jan;35(1):76-87
Molecular and cellular biology 2015 Jan;35(1):76-87
ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions.
Margaron Y, Fradet N, Côté JF
The Journal of biological chemistry 2013 Jan 11;288(2):1184-99
The Journal of biological chemistry 2013 Jan 11;288(2):1184-99
Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2.
Ho E, Dagnino L
Molecular biology of the cell 2012 Feb;23(3):492-502
Molecular biology of the cell 2012 Feb;23(3):492-502
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS
Cell 2001 Oct 5;107(1):27-41
Cell 2001 Oct 5;107(1):27-41
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS
Cell 2001 Oct 5;107(1):27-41
Cell 2001 Oct 5;107(1):27-41
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ELMO2 Antibody [NB100-879] - Analysis of ELMO in Human Brain lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ELMO2 Antibody [NB100-879] - Staining of Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
