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LearnAPR02583G
antibody from Leading Biology
Targeting: TNFRSF1A
CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60
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- Antibody Data
- Antigen structure
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- Product number
- APR02583G - Provider product page
- Provider
- Leading Biology
- Product name
- TNFRSF1A / TNFR1 Antibody
- Antibody type
- Polyclonal
- Description
- Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Drosophila, Hamster, Porcine, Rabbit, Sheep, Simian, Xenopus, Yeast
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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