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- References [5]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 22589-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PRICKLE1 antibody
- Antibody type
- Polyclonal
- Description
- PRICKLE1 antibody (Cat. #22589-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mutation of the murine Prickle1 (R104Q) causes phenotypes analogous to human symptoms of epilepsy and autism.
Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex.
PRICKLE1, a Wnt/PCP signaling component, is overexpressed and associated with inferior prognosis in acute myeloid leukemia.
The formation of paranodal spirals at the ends of CNS myelin sheaths requires the planar polarity protein Vangl2.
Coupling of apical-basal polarity and planar cell polarity to interpret the Wnt signaling gradient in feather development.
Ban Y, Yu T, Wang J, Wang X, Liu C, Baker C, Zou Y
Experimental neurology 2022 Jan;347:113880
Experimental neurology 2022 Jan;347:113880
Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex.
Ban Y, Yu T, Feng B, Lorenz C, Wang X, Baker C, Zou Y
Science advances 2021 Oct 8;7(41):eabh2974
Science advances 2021 Oct 8;7(41):eabh2974
PRICKLE1, a Wnt/PCP signaling component, is overexpressed and associated with inferior prognosis in acute myeloid leukemia.
Jiang D, He Y, Mo Q, Liu E, Li X, Huang L, Zhang Q, Chen F, Li Y, Shao H
Journal of translational medicine 2021 May 17;19(1):211
Journal of translational medicine 2021 May 17;19(1):211
The formation of paranodal spirals at the ends of CNS myelin sheaths requires the planar polarity protein Vangl2.
Jarjour AA, Velichkova AN, Boyd A, Lord KM, Torsney C, Henderson DJ, Ffrench-Constant C
Glia 2020 Sep;68(9):1840-1858
Glia 2020 Sep;68(9):1840-1858
Coupling of apical-basal polarity and planar cell polarity to interpret the Wnt signaling gradient in feather development.
Lin J, Yue Z
Development (Cambridge, England) 2018 Sep 14;145(17)
Development (Cambridge, England) 2018 Sep 14;145(17)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 22589-1-AP(PRICKLE1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRICKLE1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PRICKLE1. This antibody recognizes human, mouse antigen. The PRICKLE1 antibody has been validated for the following applications: ELISA, WB, IP analysis.
