CABT-B8496

antibody from Creative Diagnostics

Targeting: ACACB ACC2, ACCB, HACC275

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B8496

Provider

Creative Diagnostics

Product name

Anti-ACACB (aa 217-231) polyclonal antibody

Antibody type

Polyclonal

Description

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

Reactivity

Human, Mouse, Rat, Simian

Host

Goat

Conjugate

Unconjugated

Concentration

0.5 mg/mL

Storage

Store at -20°C. Minimize freezing and thawing.