HPA006554

antibody from Atlas Antibodies

Targeting: ACACB ACC2, ACCB, HACC275

Western blot (Data presented on provider website)

Immunohistochemistry (Enhanced validation)

Antibody Data

Product number

HPA006554

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA006554, RRID:AB_1844495

Product name

Anti-ACACB

Antibody type

Polyclonal

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

ITKSKSEANLIPSQEPFPASDNSGETPQRNGEGHT
LPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPR
NPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSS
ARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFD
DYSS


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.

Ma L, Murea M, Snipes JA, Marinelarena A, Krüger J, Hicks PJ, Langberg KA, Bostrom MA, Cooke JN, Suzuki D, Babazono T, Uzu T, Tang SC, Mondal AK, Sharma NK, Kobes S, Antinozzi PA, Davis M, Das SK, Rasouli N, Kern PA, Shores NJ, Rudel LL, Blüher M, Stumvoll M, Bowden DW, Maeda S, Parks JS, Kovacs P, Hanson RL, Baier LJ, Elbein SC, Freedman BI
PloS one 2013;8(2):e56193

Immunohistochemistry

Enhanced validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human adipose tissue and cerebral cortex tissues using Anti-ACACB antibody. Corresponding ACACB RNA-seq data are presented for the same tissues.

Sample type

HUMAN

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human adipose tissue shows high expression.

Sample type

HUMAN

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human cerebral cortex shows low expression as expected.

Sample type

HUMAN