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- Antigen structure
- References [18]
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- Product number
- 14221-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14221-1-AP, RRID:AB_2221547
- Product name
- ACTN2 antibody
- Antibody type
- Polyclonal
- Description
- ACTN2 antibody (Cat. #14221-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Modulation of Titin and Contraction-Regulating Proteins in a Rat Model of Heart Failure with Preserved Ejection Fraction: Limb vs. Diaphragmatic Muscle.
Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.
Exoskeleton Partial-Coated Stem Cells for Infarcted Myocardium Restoring.
Essential role of MESP1-RING1A complex in cardiac differentiation.
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells.
Microskeletal stiffness promotes aortic aneurysm by sustaining pathological vascular smooth muscle cell mechanosensation via Piezo1.
A catechol bioadhesive for rapid hemostasis and healing of traumatic internal organs and major arteries.
Identification of differential microRNAs and messenger RNAs resulting from ASXL transcriptional regulator 3 knockdown during during heart development.
Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Targeting of CAT and VCAM1 as Novel Therapeutic Targets for DMD Cardiomyopathy.
A ceRNA-associated risk model predicts the poor prognosis for head and neck squamous cell carcinoma patients.
Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes.
LncRNA-Mhrt regulates cardiac hypertrophy by modulating the miR-145a-5p/KLF4/myocardin axis.
Biomimetic electrical stimulation induces rat bone marrow mesenchymal stem cells to differentiate into cardiomyocyte-like cells via TGF-beta 1 in vitro.
Possible mechanism of GATA4 inhibiting myocardin activity during cardiac hypertrophy.
MiR-466h-5p induces expression of myocardin with complementary promoter sequences.
Early Deсline in Rat Soleus Passive Tension with Hindlimb Unloading: Inactivation of Cross-bridges or Activation of Calpains?
Vahle B, Heilmann L, Schauer A, Augstein A, Jarabo MP, Barthel P, Mangner N, Labeit S, Bowen TS, Linke A, Adams V
International journal of molecular sciences 2024 Jun 16;25(12)
International journal of molecular sciences 2024 Jun 16;25(12)
Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.
Hitachi K, Kiyofuji Y, Yamaguchi H, Nakatani M, Inui M, Tsuchida K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22692
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22692
Exoskeleton Partial-Coated Stem Cells for Infarcted Myocardium Restoring.
He H, Yuan Y, Wu Y, Lu J, Yang X, Lu K, Liu A, Cao Z, Sun M, Yu M, Wang H
Advanced materials (Deerfield Beach, Fla.) 2023 Dec;35(52):e2307169
Advanced materials (Deerfield Beach, Fla.) 2023 Dec;35(52):e2307169
Essential role of MESP1-RING1A complex in cardiac differentiation.
Liang Q, Wang S, Zhou X, Li Y, Xing S, Sha Y, Yang F, Huang W, Liu N, Li Z, Chen Y, Xu Y, Zhu P, Lan F, Sun N
Developmental cell 2022 Nov 21;57(22):2533-2549.e7
Developmental cell 2022 Nov 21;57(22):2533-2549.e7
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart.
Hulikova A, Park KC, Loonat AA, Gunadasa-Rohling M, Curtis MK, Chung YJ, Wilson A, Carr CA, Trafford AW, Fournier M, Moshnikova A, Andreev OA, Reshetnyak YK, Riley PR, Smart N, Milne TA, Crump NT, Swietach P
Basic research in cardiology 2022 Mar 31;117(1):17
Basic research in cardiology 2022 Mar 31;117(1):17
Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells.
Long C, Guo R, Han R, Li K, Wan Y, Xu J, Gong X, Zhao Y, Yao X, Liu J
Cell communication and signaling : CCS 2022 Jul 18;20(1):108
Cell communication and signaling : CCS 2022 Jul 18;20(1):108
Microskeletal stiffness promotes aortic aneurysm by sustaining pathological vascular smooth muscle cell mechanosensation via Piezo1.
Qian W, Hadi T, Silvestro M, Ma X, Rivera CF, Bajpai A, Li R, Zhang Z, Qu H, Tellaoui RS, Corsica A, Zias AL, Garg K, Maldonado T, Ramkhelawon B, Chen W
Nature communications 2022 Jan 26;13(1):512
Nature communications 2022 Jan 26;13(1):512
A catechol bioadhesive for rapid hemostasis and healing of traumatic internal organs and major arteries.
Wang G, Meng X, Wang P, Wang X, Liu G, Wang DA, Fan C
Biomaterials 2022 Dec;291:121908
Biomaterials 2022 Dec;291:121908
Identification of differential microRNAs and messenger RNAs resulting from ASXL transcriptional regulator 3 knockdown during during heart development.
Liu ZQ, Cheng M, Fu F, Li R, Han J, Yang X, Deng Q, Li LS, Lei TY, Li DZ, Liao C
Bioengineered 2022 Apr;13(4):9948-9961
Bioengineered 2022 Apr;13(4):9948-9961
Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Gilbert G, Kadur Nagaraju C, Duelen R, Amoni M, Bobin P, Eschenhagen T, Roderick HL, Sampaolesi M, Sipido KR
Frontiers in cell and developmental biology 2021;9:737840
Frontiers in cell and developmental biology 2021;9:737840
Targeting of CAT and VCAM1 as Novel Therapeutic Targets for DMD Cardiomyopathy.
Li B, Xiong W, Liang WM, Chiou JS, Lin YJ, Chang ACY
Frontiers in cell and developmental biology 2021;9:659177
Frontiers in cell and developmental biology 2021;9:659177
A ceRNA-associated risk model predicts the poor prognosis for head and neck squamous cell carcinoma patients.
Xu Y, Xu F, Lv Y, Wang S, Li J, Zhou C, Jiang J, Xie B, He F
Scientific reports 2021 Mar 18;11(1):6374
Scientific reports 2021 Mar 18;11(1):6374
Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes.
Schuldt M, Johnston JR, He H, Huurman R, Pei J, Harakalova M, Poggesi C, Michels M, Kuster DWD, Pinto JR, van der Velden J
Journal of molecular and cellular cardiology 2021 Jan;150:77-90
Journal of molecular and cellular cardiology 2021 Jan;150:77-90
LncRNA-Mhrt regulates cardiac hypertrophy by modulating the miR-145a-5p/KLF4/myocardin axis.
Xu Y, Luo Y, Liang C, Zhang T
Journal of molecular and cellular cardiology 2020 Feb;139:47-61
Journal of molecular and cellular cardiology 2020 Feb;139:47-61
Biomimetic electrical stimulation induces rat bone marrow mesenchymal stem cells to differentiate into cardiomyocyte-like cells via TGF-beta 1 in vitro.
He X, Li L, Tang M, Zeng Y, Li H, Yu X
Progress in biophysics and molecular biology 2019 Nov;148:47-53
Progress in biophysics and molecular biology 2019 Nov;148:47-53
Possible mechanism of GATA4 inhibiting myocardin activity during cardiac hypertrophy.
Xu Y, Liang C, Luo Y, Xing W, Zhang T
Journal of cellular biochemistry 2019 Jun;120(6):9047-9055
Journal of cellular biochemistry 2019 Jun;120(6):9047-9055
MiR-466h-5p induces expression of myocardin with complementary promoter sequences.
Luo Y, Liang C, Xu Y, Zhang T
Biochemical and biophysical research communications 2019 Jun 18;514(1):187-193
Biochemical and biophysical research communications 2019 Jun 18;514(1):187-193
Early Deсline in Rat Soleus Passive Tension with Hindlimb Unloading: Inactivation of Cross-bridges or Activation of Calpains?
Petrova IO, Tyganov SA, Mirzoev TM, Tsaturyan AK, Kozlovskaya IB, Shenkman BS
Doklady. Biochemistry and biophysics 2018 Jul;481(1):205-207
Doklady. Biochemistry and biophysics 2018 Jul;481(1):205-207
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACTN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACTN2. This antibody recognizes human, mouse, rat antigen. The ACTN2 antibody has been validated for the following applications: ELISA, WB analysis.
