ABIN151138

antibody from antibodies-online

Targeting: UBR5 DD5, EDD, EDD1, HYD, KIAA0896

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN151138

Provider

antibodies-online

Product name

anti-Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) (AA 600-650) antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 600-650

Vial size

100 μL

Storage

Store at 4°C. Do not freeze.

Handling

Do not freeze.

References

Submitted references

Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF-α-dependent necroptosis driven by RIP1 kinase and NF-κB.

Oliver Metzig M, Fuchs D, Tagscherer KE, Gröne HJ, Schirmacher P, Roth W
Oncogene 2016 Jun 30;35(26):3399-409

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Immunohistochemical analysis of Marinesco bodies, using antibodies against proteins implicated in the ubiquitin-proteasome system, autophagy and aggresome formation.

Odagiri S, Tanji K, Mori F, Kakita A, Takahashi H, Kamitani T, Wakabayashi K
Neuropathology : official journal of the Japanese Society of Neuropathology 2012 Jun;32(3):261-6

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A novel role for RIP1 kinase in mediating TNFα production.

Christofferson DE, Li Y, Hitomi J, Zhou W, Upperman C, Zhu H, Gerber SA, Gygi S, Yuan J
Cell death & disease 2012 Jun 14;3:e320

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A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis.

Dompe N, Rivers CS, Li L, Cordes S, Schwickart M, Punnoose EA, Amler L, Seshagiri S, Tang J, Modrusan Z, Davis DP
Proceedings of the National Academy of Sciences of the United States of America 2011 Oct 25;108(43):E943-51

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EDD inhibits ATM-mediated phosphorylation of p53.

Ling S, Lin WC
The Journal of biological chemistry 2011 Apr 29;286(17):14972-82

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Identification of cellular proteins that interact with the adeno-associated virus rep protein.

Nash K, Chen W, Salganik M, Muzyczka N
Journal of virology 2009 Jan;83(1):454-69

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The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.

O'Brien PM, Davies MJ, Scurry JP, Smith AN, Barton CA, Henderson MJ, Saunders DN, Gloss BS, Patterson KI, Clancy JL, Heinzelmann-Schwarz VA, Murali R, Scolyer RA, Zeng Y, Williams ED, Scurr L, Defazio A, Quinn DI, Watts CK, Hacker NF, Henshall SM, Sutherland RL
British journal of cancer 2008 Mar 25;98(6):1085-93

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunocytochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

ICC

Immunoprecipitation

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IP

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC