Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [4]
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Validation data
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- Product number
- NBP1-84026 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-84026, RRID:AB_11016341
- Product name
- Rabbit Polyclonal EYA2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human EYA2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references A phosphotyrosine switch determines the antitumor activity of ERβ.
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.
Yuan B, Cheng L, Chiang HC, Xu X, Han Y, Su H, Wang L, Zhang B, Lin J, Li X, Xie X, Wang T, Tekmal RR, Curiel TJ, Yuan ZM, Elledge R, Hu Y, Ye Q, Li R
The Journal of clinical investigation 2014 Aug;124(8):3378-90
The Journal of clinical investigation 2014 Aug;124(8):3378-90
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.
Farabaugh SM, Micalizzi DS, Jedlicka P, Zhao R, Ford HL
Oncogene 2012 Feb 2;31(5):552-62
Oncogene 2012 Feb 2;31(5):552-62
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: EYA2 Antibody [NBP1-84026] - Analysis in human cell line SCLC-21H.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: EYA2 Antibody [NBP1-84026] - Analysis in human cell line SCLC-21H.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: EYA2 Antibody [NBP1-84026] - Staining of human cervix, uterine shows strong nuclear positivity in squamous epithelial cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: EYA2 Antibody [NBP1-84026] - Staining of human liver shows weak to moderate nuclear positivity in hepatocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: EYA2 Antibody [NBP1-84026] - Staining of human stomach shows strong nuclear positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: EYA2 Antibody [NBP1-84026] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.