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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
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- Product number
- HPA026745 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA026745, RRID:AB_1855520
- Product name
- Anti-POLD2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human POLD2, Gene description: polymerase (DNA directed), delta 2, accessory subunit, Validated applications: ICC, IHC, WB, Uniprot ID: P49005, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
Human Autosomal Recessive DNA Polymerase Delta 3 Deficiency Presenting as Omenn Syndrome
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components
Combined immunodeficiency caused by a loss-of-function mutation in DNA polymerase delta 1
Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair
Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress
Ratnayeke N, Baris Y, Chung M, Yeeles J, Meyer T
Molecular Cell 2023;83(1):26-42.e13
Molecular Cell 2023;83(1):26-42.e13
Human Autosomal Recessive DNA Polymerase Delta 3 Deficiency Presenting as Omenn Syndrome
Riestra M, Pillay B, Willemsen M, Kienapfel V, Ehlers L, Delafontaine S, Pinton A, Wouters M, Hombrouck A, Sauer K, Bossuyt X, Voet A, Soenen S, Conde C, Bucciol G, Boztug K, Humblet-Baron S, Touzart A, Rieux-Laucat F, Notarangelo L, Moens L, Meyts I
Journal of Clinical Immunology 2023;44(1)
Journal of Clinical Immunology 2023;44(1)
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components
Fan Y, Köberlin M, Ratnayeke N, Liu C, Deshpande M, Gerhardt J, Meyer T
Journal of Cell Biology 2021;220(8)
Journal of Cell Biology 2021;220(8)
Combined immunodeficiency caused by a loss-of-function mutation in DNA polymerase delta 1
Cui Y, Keles S, Charbonnier L, Julé A, Henderson L, Celik S, Reisli I, Shen C, Xie W, Schmitz-Abe K, Wu H, Chatila T
Journal of Allergy and Clinical Immunology 2020;145(1):391-401.e8
Journal of Allergy and Clinical Immunology 2020;145(1):391-401.e8
Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair
Layer J, Debaize L, Van Scoyk A, House N, Brown A, Liu Y, Stevenson K, Hemann M, Roberts S, Price B, Weinstock D, Day T
Proceedings of the National Academy of Sciences 2020;117(44):27566-27577
Proceedings of the National Academy of Sciences 2020;117(44):27566-27577
Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress
Conde C, Petronczki Ö, Baris S, Willmann K, Girardi E, Salzer E, Weitzer S, Ardy R, Krolo A, Ijspeert H, Kiykim A, Karakoc-Aydiner E, Förster-Waldl E, Kager L, Pickl W, Superti-Furga G, Martínez J, Loizou J, Ozen A, van der Burg M, Boztug K
Journal of Clinical Investigation 2019;129(10):4194-4206
Journal of Clinical Investigation 2019;129(10):4194-4206
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in U2OS cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-POLD2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
