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- Product number
- ABIN4948223 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 324-424) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 324-424
- Isotype
- IgG
- Antibody clone number
- 4E2
- Vial size
- 50 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program.
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Variants in hepatocyte nuclear factor 4alpha gene promoter region and type 2 diabetes risk in Chinese.
The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.
Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism.
Jablonski KA, McAteer JB, de Bakker PI, Franks PW, Pollin TI, Hanson RL, Saxena R, Fowler S, Shuldiner AR, Knowler WC, Altshuler D, Florez JC, Diabetes Prevention Program Research Group.
Diabetes 2010 Oct;59(10):2672-81
Diabetes 2010 Oct;59(10):2672-81
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators.
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
Variants in hepatocyte nuclear factor 4alpha gene promoter region and type 2 diabetes risk in Chinese.
Chen Z, Zhang D, Liu Y, Zhou D, Zhao T, Yang Y, He L, Xu H
Experimental biology and medicine (Maywood, N.J.) 2010 Jul;235(7):857-61
Experimental biology and medicine (Maywood, N.J.) 2010 Jul;235(7):857-61
The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.
de Boussac H, Ratajewski M, Sachrajda I, Köblös G, Tordai A, Pulaski L, Buday L, Váradi A, Arányi T
The Journal of biological chemistry 2010 Jul 23;285(30):22800-8
The Journal of biological chemistry 2010 Jul 23;285(30):22800-8
Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism.
Ruchat SM, Vohl MC, Weisnagel SJ, Rankinen T, Bouchard C, Pérusse L
Annals of medicine 2010 Apr;42(3):196-206
Annals of medicine 2010 Apr;42(3):196-206
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