BS60801

antibody from Bioworld Technology, Inc
Targeting: CELSR3 ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2
Provider product page for BS60801

Antibody data

Product number
BS60801 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CELSR3 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human CELSR3.
Description
Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development, during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, and show expression patterns in the developing CNS. CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells and olfactory neurons.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CELSR3 protein structure - BS60801 shown in red.