BS1401

antibody from Bioworld Technology, Inc
Targeting: NR3C1 GR, GRL
Provider product page for BS1401
Western blot
Immunohistochemistry

Antibody data

Product number
BS1401 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1401, RRID:AB_1663489
Product name
GR (L224) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 201-250 of Human GR.
Description
The glucocorticoid receptor (GR) is an ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GRÏ«. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis and cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the nonligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.
Reactivity
Human, Mouse, Rat, Porcine
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NR3C1 protein structure - BS1401 shown in red.