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- References [4]
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- Product number
- ABIN500622 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ribonuclease H2, Subunit A (RNASEH2A) antibody
- Antibody type
- Polyclonal
- Antigen
- RNAse H2A antibody was raised against a 17 amino acid peptide near the center of humanRNAse H2A.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references Ribonuclease H: the enzymes in eukaryotes.
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.
RNase H2 of Saccharomyces cerevisiae is a complex of three proteins.
Enzyme from calf thymus degrading the RNA moiety of DNA-RNA Hybrids: effect on DNA-dependent RNA polymerase.
Cerritelli SM, Crouch RJ
The FEBS journal 2009 Mar;276(6):1494-505
The FEBS journal 2009 Mar;276(6):1494-505
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.
Crow YJ, Leitch A, Hayward BE, Garner A, Parmar R, Griffith E, Ali M, Semple C, Aicardi J, Babul-Hirji R, Baumann C, Baxter P, Bertini E, Chandler KE, Chitayat D, Cau D, Déry C, Fazzi E, Goizet C, King MD, Klepper J, Lacombe D, Lanzi G, Lyall H, Martínez-Frías ML, Mathieu M, McKeown C, Monier A, Oade Y, Quarrell OW, Rittey CD, Rogers RC, Sanchis A, Stephenson JB, Tacke U, Till M, Tolmie JL, Tomlin P, Voit T, Weschke B, Woods CG, Lebon P, Bonthron DT, Ponting CP, Jackson AP
Nature genetics 2006 Aug;38(8):910-6
Nature genetics 2006 Aug;38(8):910-6
RNase H2 of Saccharomyces cerevisiae is a complex of three proteins.
Jeong HS, Backlund PS, Chen HC, Karavanov AA, Crouch RJ
Nucleic acids research 2004;32(2):407-14
Nucleic acids research 2004;32(2):407-14
Enzyme from calf thymus degrading the RNA moiety of DNA-RNA Hybrids: effect on DNA-dependent RNA polymerase.
Stein H, Hausen P
Science (New York, N.Y.) 1969 Oct 17;166(3903):393-5
Science (New York, N.Y.) 1969 Oct 17;166(3903):393-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of RNAse H2A in HeLa cell lysate with AP30734PU-N at 1 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of RNAse H2A in HeLa cells with AP30734PU-N at 2 ?g/ml.
