Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [10]
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- Product number
- NBP1-82976 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-82976, RRID:AB_11012626
- Product name
- Rabbit Polyclonal G3BP2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human sG3BP2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.
4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer.
Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway.
Ramachandran B, Stabley JN, Cheng SL, Behrmann AS, Gay A, Li L, Mead M, Kozlitina J, Lemoff A, Mirzaei H, Chen Z, Towler DA
The Journal of biological chemistry 2018 May 25;293(21):7942-7968
The Journal of biological chemistry 2018 May 25;293(21):7942-7968
4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer.
De Marchi T, Liu NQ, Stingl C, Timmermans MA, Smid M, Look MP, Tjoa M, Braakman RB, Opdam M, Linn SC, Sweep FC, Span PN, Kliffen M, Luider TM, Foekens JA, Martens JW, Umar A
Molecular oncology 2016 Jan;10(1):24-39
Molecular oncology 2016 Jan;10(1):24-39
Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway.
Wei SC, Fattet L, Tsai JH, Guo Y, Pai VH, Majeski HE, Chen AC, Sah RL, Taylor SS, Engler AJ, Yang J
Nature cell biology 2015 May;17(5):678-88
Nature cell biology 2015 May;17(5):678-88
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: G3BP2 Antibody [NBP1-82976] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: G3BP2 Antibody [NBP1-82976] - Analysis in human cell line SH-SY5Y.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human cerebral cortex shows high expression.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human skin shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining in human cerebral cortex and skin tissues using anti-G3BP2 antibody. Corresponding G3BP2 RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells and cells in molecular layer.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human cerebellum, cerebral cortex, skin and testis using Anti-G3BP2 antibody NBP1-82976 (A) shows similar protein distribution across tissues to independent antibody NBP1-82977 (B).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human testis using Anti-G3BP2 antibody NBP1-82976.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human cerebellum using Anti-G3BP2 antibody NBP1-82976.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human cerebral cortex using Anti-G3BP2 antibody NBP1-82976.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: G3BP2 Antibody [NBP1-82976] - Staining of human skin using Anti-G3BP2 antibody NBP1-82976.