BS6510

antibody from Bioworld Technology, Inc
Targeting: ACP3 ACP-3, ACPP, PAP, TM-PAP
Provider product page for BS6510
Western blot
Immunohistochemistry

Antibody data

Product number
BS6510 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ACPP polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ACPP.
Description
Human prostatic acid phosphatase (also known as PAcP, PAP, PPAP, ACPP) is a prostate epithelium-specific differentiation antigen. The cellular form of PAcP functions as a neutral protein-tyrosine phosphatase, and is involved in regulating prostate cell growth. Specifically, PAcP catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. PAcP is synthesized under androgen regulation. The stimulated secretion of prostatic acid phosphatase is a hallmark of androgen action on human prostate epithelial cells, implicating PAcP as a useful tool in identifying atrophy of prostatic tissue. Cellular PAcP can down-regulate prostate cancer cell growth, at least partially by dephosphorylating c-ErbB-2/neu. Therefore, decreased cellular PAcP expression in cancer cells may be involved in prostate cancer progression. PAcP is the protein product of the human ACPP gene, which maps to chromosome 3q21-q23.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ACP3 protein structure - BS6510 shown in red.