NBP2-19051

antibody from Novus Biologicals

Targeting: CDH1 CD324, UVO, uvomorulin

Provider product page for NBP2-19051

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [15]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]
Flow cytometry [1]

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Product number: NBP2-19051 - Provider product page
Provider: Novus Biologicals
Product name: Mouse Monoclonal E-Cadherin Antibody
Antibody type: Monoclonal
Description: Unpurified.
Reactivity: Human, Mouse, Simian
Host: Mouse
Isotype: IgG
Vial size: 0.1 ml
Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

CDH1 protein structure - NBP2-19051 shown in red.

Submitted references miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1.

Chu JYS, Chau MKM, Chan CCY, Tai ACP, Cheung KF, Chan TM, Yung S
Molecular therapy. Nucleic acids 2019 Sep 6;17:78-91

Microporous scaffolds support assembly and differentiation of pancreatic progenitors into β-cell clusters.

Youngblood RL, Sampson JP, Lebioda KR, Shea LD
Acta biomaterialia 2019 Sep 15;96:111-122

Cadmium exposure upregulates SNAIL through miR-30 repression in human lung epithelial cells.

Tanwar VS, Zhang X, Jagannathan L, Jose CC, Cuddapah S
Toxicology and applied pharmacology 2019 Jun 15;373:1-9

Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery.

Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, Zhao X, Lu C
Journal of experimental & clinical cancer research : CR 2019 Feb 8;38(1):62

Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.

Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A
Cell metabolism 2019 Aug 6;30(2):385-401.e9

AngII induces HepG2 cells to activate epithelial-mesenchymal transition.

Qi M, Zhou Y, Liu J, Ou X, Li M, Long X, Ye J, Yu G
Experimental and therapeutic medicine 2018 Oct;16(4):3471-3477

Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1.

Jose CC, Jagannathan L, Tanwar VS, Zhang X, Zang C, Cuddapah S
Molecular carcinogenesis 2018 Jun;57(6):794-806

Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.

Chuang CH, Wang LY, Wong YM, Lin ES
Oncology letters 2018 Apr;15(4):4690-4696

Size-dependent Effects of Gold Nanoparticles on Osteogenic Differentiation of Human Periodontal Ligament Progenitor Cells.

Zhang Y, Kong N, Zhang Y, Yang W, Yan F
Theranostics 2017;7(5):1214-1224

Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport.

Thamotharan S, Chu A, Kempf K, Janzen C, Grogan T, Elashoff DA, Devaskar SU
PloS one 2017;12(5):e0176493

E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer.

Liao L, Song M, Li X, Tang L, Zhang T, Zhang L, Pan Y, Chouchane L, Ma X
Cancer research 2017 Apr 15;77(8):2090-2101

Glucocorticoid receptor-mediated delivery of nano gold-withaferin conjugates for reversal of epithelial-to-mesenchymal transition and tumor regression.

Agarwalla P, Mukherjee S, Sreedhar B, Banerjee R
Nanomedicine (London, England) 2016 Oct;11(19):2529-46

Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.

Mondal SK, Jinka S, Pal K, Nelli S, Dutta SK, Wang E, Ahmad A, AlKharfy KM, Mukhopadhyay D, Banerjee R
Molecular pharmaceutics 2016 Jul 5;13(7):2507-23

Downregulation of HMGA2 inhibits cellular proliferation and invasion, improves cellular apoptosis in prostate cancer.

Cai J, Shen G, Liu S, Meng Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):699-707

Molecular mechanisms underlying human adipose tissue-derived stromal cells differentiation into a hepatocyte-like phenotype.

Saulnier N, Piscaglia AC, Puglisi MA, Barba M, Arena V, Pani G, Alfieri S, Gasbarrini A
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2010 Dec;42(12):895-901

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Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Western Blot: E-Cadherin Antibody (7H12) [NBP2-19051] - Analysis of E-Cadherin in LNCAP (1), A431 (2), DU145 (3), PC-3 (4), MCF-7 (5), PC-12 (6), NIH/3T3 (7), C6 (8) and COS7 (9) cell lysate.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: E-Cadherin Antibody (7H12) [NBP2-19051] - IHC staining of E-Cadherin in gastric cancer tissues (left) and lung cancer tissues (right) with DAB staining.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Immunohistochemistry-Paraffin: E-Cadherin Antibody (7H12) [NBP2-19051] - Human kidney distal tubules stained with E-CAD antibody. Secondary antibody: Donkey anti-Mouse Alexa Fluor 555. Imaging with a 40x objective from Zeiss Observer microscope with Apotome2. Image from verified customer review.

Supportive validation

Submitted by: Novus Biologicals (provider)
Main image
Experimental details: Flow Cytometry: E-Cadherin Antibody (7H12) [NBP2-19051] - Analysis of Hela cells using E-Cadherin mouse mAb (green) and negative control (purple).