60157

antibody from STEMCELL Technologies Inc
Targeting: CDH1 CD324, UVO, uvomorulin
Provider product page for 60157
Immunocytochemistry
Immunoprecipitation
Flow cytometry

Antibody data

Product number
60157 - Provider product page
Provider
STEMCELL Technologies Inc
Product name
Anti-Mouse E-Cadherin (CD324) Antibody, Clone DECMA-1
Antibody type
Monoclonal
Description
The DECMA-1 antibody recognizes E-cadherin, a calcium-dependent transmembrane glycoprotein involved in cell-cell adhesion, bacterial pathogenesis, and tumor invasion. The extracellular region of E-cadherin is composed of multiple cadherin repeats that contain calcium-binding motifs. The cytoplasmic domain of E-cadherin is reported to interact with a range of intracellular proteins including erbin, ezrin, caspase-3, caspase-8, ?-catenin, presenilin 1, and casein kinase II. E-cadherin is expressed in most epithelial cells and in erythroid cells. The E-cadherin antibody is often used as a neutralizing antibody to inhibit E-cadherin-mediated cell-cell interactions.
Reactivity
Human, Mouse, Canine, Porcine
Vial size
100 µg
Storage
2 - 8°C
CDH1 protein structure - 60157 shown in red.