Ab100725

antibody from Aladdin Scientific Corporation

Targeting: CDH1 CD324, UVO, uvomorulin

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab100725

Provider

Aladdin Scientific Corporation

Product name

E Cadherin Mouse mAb

Antibody type

Monoclonal

Description

Mouse monoclonal (7H12) to E Cadherin, could be used for WB, IHC and Flow.Application  WB: 1/500-1/2000 IHC: 1/200-1/1000Flow: 1/200-1/400ELISA: 1/10000PurityProtein G purified.Protein FunctionCadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

Reactivity

Human, Mouse, Rat, Simian

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

AA: DWVIPPISCPENEKC


Isotype

IgG

Antibody clone number

7H12

Vial size

100μl,10μl,1ml,50μl

Concentration

1 mg/ml

Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Stable for 12 months at -20°C.