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- References [8]
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- Western blot [1]
- Immunohistochemistry [15]
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- Product number
- NBP1-88219 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-88219, RRID:AB_11011221
- Product name
- Rabbit Polyclonal Secretagogin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human, mouse Secretagogin antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.
Distribution of secretagogin-containing neurons in the basal forebrain of mice, with special reference to the cholinergic corticopetal system.
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
The renaissance of Ca2+-binding proteins in the nervous system: secretagogin takes center stage.
Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation.
Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon.
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Secretagogin is a Ca2+-binding protein specifying subpopulations of telencephalic neurons.
Zhang MD, Tortoriello G, Hsueh B, Tomer R, Ye L, Mitsios N, Borgius L, Grant G, Kiehn O, Watanabe M, Uhlén M, Mulder J, Deisseroth K, Harkany T, Hökfelt TG
Proceedings of the National Academy of Sciences of the United States of America 2014 Mar 25;111(12):E1149-58
Proceedings of the National Academy of Sciences of the United States of America 2014 Mar 25;111(12):E1149-58
Distribution of secretagogin-containing neurons in the basal forebrain of mice, with special reference to the cholinergic corticopetal system.
Gyengesi E, Andrews ZB, Paxinos G, Zaborszky L
Brain research bulletin 2013 May;94:1-8
Brain research bulletin 2013 May;94:1-8
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
Lindskog C, Korsgren O, Pontén F, Eriksson JW, Johansson L, Danielsson A
Journal of proteomics 2012 May 17;75(9):2611-20
Journal of proteomics 2012 May 17;75(9):2611-20
The renaissance of Ca2+-binding proteins in the nervous system: secretagogin takes center stage.
Alpár A, Attems J, Mulder J, Hökfelt T, Harkany T
Cellular signalling 2012 Feb;24(2):378-87
Cellular signalling 2012 Feb;24(2):378-87
Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation.
Attems J, Alpar A, Spence L, McParland S, Heikenwalder M, Uhlén M, Tanila H, Hökfelt TG, Harkany T
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 17;109(16):6259-64
Proceedings of the National Academy of Sciences of the United States of America 2012 Apr 17;109(16):6259-64
Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon.
Mulder J, Spence L, Tortoriello G, Dinieri JA, Uhlén M, Shui B, Kotlikoff MI, Yanagawa Y, Aujard F, Hökfelt T, Hurd YL, Harkany T
The European journal of neuroscience 2010 Jun;31(12):2166-77
The European journal of neuroscience 2010 Jun;31(12):2166-77
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Mulder J, Björling E, Jonasson K, Wernérus H, Hober S, Hökfelt T, Uhlén M
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
Secretagogin is a Ca2+-binding protein specifying subpopulations of telencephalic neurons.
Mulder J, Zilberter M, Spence L, Tortoriello G, Uhlén M, Yanagawa Y, Aujard F, Hökfelt T, Harkany T
Proceedings of the National Academy of Sciences of the United States of America 2009 Dec 29;106(52):22492-7
Proceedings of the National Academy of Sciences of the United States of America 2009 Dec 29;106(52):22492-7
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Secretagogin Antibody [NBP1-88219] - Analysis in human cerebellum tissue.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Secretagogin Antibody [NBP1-88219] - Staining of human pancreas shows strong cytoplasmic and nuclear positivity in islets of Langerhans.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Secretagogin Antibody [NBP1-88219] - Staining of human pancreas shows strong cytoplasmic and nuclear positivity in islets of Langerhans.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Secretagogin Antibody [NBP1-88219] - Staining of human hippocampus shows strong positivity in subsets of neuronal cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Secretagogin Antibody [NBP1-88219] - Staining human cerebellum shows strong immunoreactivity in the molecular layer neurons.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Secretagogin Antibody [NBP1-88219] - Staining mouse brain shows selective immunoreactivity in fasciola cinerera.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Secretagogin Antibody [NBP1-88219] - Staining mouse hypothalamus shows selective positivity in the periventricular nucleus.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Secretagogin Antibody [NBP1-88219] - Staining mouse septohippocampal nucleus shows labeling of neuronal cell bodies and processes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining of mouse brain shows positivity in fasciola cinereum.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining of mouse hypothalamus shows positivity in the paraventricular hypothalamic nucleus.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining of human cerebellum shows strong nuclear positivity in cells in molecular layer.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining of human Fallopian tube shows no positivity in glandular cells as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining of human pancreas shows strong cytoplasmic and nuclear positivity in islets of Langerhans.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining of human rectum shows strong cytoplasmic positivity in peripheral nerve / ganglion.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining of mouse olfactory bulb, glomerular layer shows nuclear positivity.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Secretagogin Antibody [NBP1-88219] - Staining in human pancreas and fallopian tube tissues using NBP1-88219 antibody. Corresponding SCGN RNA-seq data are presented for the same tissues.
