FNab05835

antibody from FineTest Biotech

Targeting: NR1H3 LXR-a, LXRa, RLD-1

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab05835 - Provider product page
Provider: FineTest Biotech
Product name: NR1H3 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism(By similarity). Exhibits a ligand-dependent transcriptional activation activity(PubMed:25661920).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: nuclear receptor subfamily 1, group H, member 3
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

NR1H3 protein structure - FNab05835 shown in red.