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- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500216 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-MAP-Kinase Activating Death Domain (MADD) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- MADD antibody was raised against a peptide corresponding to amino acids near thecarboxy terminus of human MADD.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system.
MADD is highly homologous to a Rab3 guanine-nucleotide exchange protein (Rab3-GEP)
MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase.
DENN, a novel human gene differentially expressed in normal and neoplastic cells.
Zhang Y, Zhou L, Miller CA
Proceedings of the National Academy of Sciences of the United States of America 1998 Mar 3;95(5):2586-91
Proceedings of the National Academy of Sciences of the United States of America 1998 Mar 3;95(5):2586-91
MADD is highly homologous to a Rab3 guanine-nucleotide exchange protein (Rab3-GEP)
Brown TL, Howe PH
Current biology : CB 1998 Mar 12;8(6):R191
Current biology : CB 1998 Mar 12;8(6):R191
MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase.
Schievella AR, Chen JH, Graham JR, Lin LL
The Journal of biological chemistry 1997 May 2;272(18):12069-75
The Journal of biological chemistry 1997 May 2;272(18):12069-75
DENN, a novel human gene differentially expressed in normal and neoplastic cells.
Chow VT, Lee SS
DNA sequence : the journal of DNA sequencing and mapping 1996;6(5):263-73
DNA sequence : the journal of DNA sequencing and mapping 1996;6(5):263-73
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of MADD in whole cell lysates from the indicated cell lines with MAAP30529PU-N at 1:250 dilution.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of MADD in human spleen tissue with AP30529PU-N at 10 ?g/ml.
