Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B9214 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human GPI-Phospholipase D monoclonal antibody, clone 26/HQJ
- Antibody type
- Monoclonal
- Description
- Glycosylphosphatidylinositol (GPI)-anchored proteins are involved in the regulation of numerous cell-surface activities including the complement cascade, activation of plasminogen, T-cell activation, cell-to-cell adhesion, and macromolecule transport through the membrane. GPI-containing proteins are very abundant at the caveolae. GPI-specific phospholipase D (GPI-PLD) hydrolyzes the covalently bound GPI moiety which functions as an anchor for many cell-surface proteins. Present at high levels in the plasma, GPI-PLD is also secreted by some cell types in culture. This protein releases the GPI-anchored, complement regulatory protein decay accelerating factor (DAF) from HeLa cells, as well as the basic fibroblast growth factor (bFGF)-bound heparin sulfate proteoglycan from bone marrow stromal cells. GPI-PLD contains Ca2+ and Zn2+ binding sites and bears some further structural and perhaps functional similarities to the integrins.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 26/HQJ
- Vial size
- 50 _g
- Concentration
- 250 Ã×g/ml
- Storage
- Store undiluted at -20°C.
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