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antibody from antibodies-online
Targeting: EXOSC10
p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p
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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [3]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN442824 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Exosome Component 10 (EXOSC10) (Center) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references An Mtr4/ZFC3H1 complex facilitates turnover of unstable nuclear RNAs to prevent their cytoplasmic transport and global translational repression.
RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells.
A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage.
Ogami K, Richard P, Chen Y, Hoque M, Li W, Moresco JJ, Yates JR 3rd, Tian B, Manley JL
Genes & development 2017 Jun 15;31(12):1257-1271
Genes & development 2017 Jun 15;31(12):1257-1271
RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells.
Hsin JP, Li W, Hoque M, Tian B, Manley JL
eLife 2014 May 8;3:e02112
eLife 2014 May 8;3:e02112
A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage.
Richard P, Feng S, Manley JL
Genes & development 2013 Oct 15;27(20):2227-32
Genes & development 2013 Oct 15;27(20):2227-32
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- Image(s): Immunofluorescence
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
