Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 20985-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20985-1-AP, RRID:AB_11182391
- Product name
- DEPDC6/Deptor antibody
- Antibody type
- Polyclonal
- Description
- DEPDC6/Deptor antibody (Cat. #20985-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LncRNA KB-1471A8.2 Overexpression Suppresses Cell Proliferation and Migration and Antagonizes the Paclitaxel Resistance of Ovarian Cancer Cells.
TNFAIP3-DEPTOR complex regulates inflammasome secretion through autophagy in ankylosing spondylitis monocytes.
The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling.
DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis.
p65 down-regulates DEPTOR expression in response to LPS stimulation in hepatocytes.
Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation.
Zhang M, Liu S, Fu C, Wang X, Zhang M, Liu G, Dai C, Gong Z, Xu H, Fu Z, Xu P, Xu J, Jia X
Cancer biotherapy & radiopharmaceuticals 2019 Jun;34(5):316-324
Cancer biotherapy & radiopharmaceuticals 2019 Jun;34(5):316-324
TNFAIP3-DEPTOR complex regulates inflammasome secretion through autophagy in ankylosing spondylitis monocytes.
Zhai Y, Lin P, Feng Z, Lu H, Han Q, Chen J, Zhang Y, He Q, Nan G, Luo X, Wang B, Feng F, Liu F, Chen Z, Zhu P
Autophagy 2018;14(9):1629-1643
Autophagy 2018;14(9):1629-1643
The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling.
Csukasi F, Duran I, Barad M, Barta T, Gudernova I, Trantirek L, Martin JH, Kuo CY, Woods J, Lee H, Cohn DH, Krejci P, Krakow D
Science translational medicine 2018 Sep 19;10(459)
Science translational medicine 2018 Sep 19;10(459)
DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis.
Chen S, Jia L, Zhang S, Zheng Y, Zhou Y
Stem cell research & therapy 2018 Jul 4;9(1):185
Stem cell research & therapy 2018 Jul 4;9(1):185
p65 down-regulates DEPTOR expression in response to LPS stimulation in hepatocytes.
Yu X, Jin D, Yu A, Sun J, Chen X, Yang Z
Gene 2016 Sep 1;589(1):12-19
Gene 2016 Sep 1;589(1):12-19
Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation.
Cheng M, Hu S, Wang Z, Pei Y, Fan R, Liu X, Wang L, Zhou J, Zheng S, Zhang T, Lin Y, Zhang M, Tao R, Zhong J
Oncotarget 2016 Jun 14;7(24):35643-35654
Oncotarget 2016 Jun 14;7(24):35643-35654
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 20985-1-AP(DEPDC6 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DEPDC6 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human DEPDC6. This antibody recognizes human,mouse,rat antigen. The DEPDC6 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 20985-1-AP(DEPDC6 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 20985-1-AP(DEPDC6 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue