Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [5]
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Validation data
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- Product number
- NBP1-90114 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-90114, RRID:AB_11028537
- Product name
- Rabbit Polyclonal actin-related protein 2/3 complex subunit 1B Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human actin-related protein 2/3 complex subunit 1B antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Lanthanum Chloride Impairs Learning and Memory and Induces Dendritic Spine Abnormality by Down-Regulating Rac1/PAK Signaling Pathway in Hippocampus of Offspring Rats.
Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B.
Isoform diversity in the Arp2/3 complex determines actin filament dynamics.
Sun W, Yang J, Hong Y, Yuan H, Wang J, Zhang Y, Lu X, Jin C, Wu S, Cai Y
Cellular and molecular neurobiology 2020 Apr;40(3):459-475
Cellular and molecular neurobiology 2020 Apr;40(3):459-475
Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B.
Somech R, Lev A, Lee YN, Simon AJ, Barel O, Schiby G, Avivi C, Barshack I, Rhodes M, Yin J, Wang M, Yang Y, Rhodes J, Marcus N, Garty BZ, Stein J, Amariglio N, Rechavi G, Wiest DL, Zhang Y
Journal of immunology (Baltimore, Md. : 1950) 2017 Dec 15;199(12):4036-4045
Journal of immunology (Baltimore, Md. : 1950) 2017 Dec 15;199(12):4036-4045
Isoform diversity in the Arp2/3 complex determines actin filament dynamics.
Abella JV, Galloni C, Pernier J, Barry DJ, Kjær S, Carlier MF, Way M
Nature cell biology 2016 Jan;18(1):76-86
Nature cell biology 2016 Jan;18(1):76-86
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: actin-related protein 2/3 complex subunit 1B Antibody [NBP1-90114] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: actin-related protein 2/3 complex subunit 1B Antibody [NBP1-90114] - Analysis in human cell lines SK-MEL-30 and HEK293 using anti-ARPC1B antibody. Corresponding ARPC1B RNA-seq data are presented for the same cell lines. Loading control: anti-HDAC1.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: actin-related protein 2/3 complex subunit 1B Antibody [NBP1-90114] - Analysis in human lymph node and skeletal muscle tissues. Corresponding ARPC1B RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: actin-related protein 2/3 complex subunit 1B Antibody [NBP1-90114] - Staining of human lung shows weak cytoplasmic positivity in macrophages.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: actin-related protein 2/3 complex subunit 1B Antibody [NBP1-90114] - Staining of human small intestine shows moderate cytoplasmic positivity in lymphoid cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: actin-related protein 2/3 complex subunit 1B Antibody [NBP1-90114] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: actin-related protein 2/3 complex subunit 1B Antibody [NBP1-90114] - Staining of human lymph node shows strong cytoplasmic positivity in germinal center cells.