BS6689

antibody from Bioworld Technology, Inc
Targeting: PDGFRA CD140a, GAS9, PDGFR2
Provider product page for BS6689
Western blot
Immunohistochemistry

Antibody data

Product number
BS6689 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PDGFR Ï« polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PDGFR-Ï«.
Description
Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PDGFRA protein structure - BS6689 shown in red.