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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [56]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Blocking/Neutralizing [1]
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- Product number
- AF1062 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal PDGFR alpha Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse PDGF R alpha in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) PDGF R alpha , rhPDGF R beta , and recombinant mouse PDGF R beta is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle.
Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration.
Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice.
Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome.
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage.
Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds.
Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration.
TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung.
In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Myelin repair stimulated by CNS-selective thyroid hormone action.
PDGFRα(+) stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α.
AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.
Pulmonary pericytes regulate lung morphogenesis.
Perfect chronic skeletal muscle regeneration in adult spiny mice, Acomys cahirinus.
Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice.
Role of P2X4 Receptor in Mouse Voiding Function.
Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner.
Profiling proliferative cells and their progeny in damaged murine hearts.
Myelination of the developing lateral olfactory tract and anterior commissure.
Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion.
B-1a lymphocytes promote oligodendrogenesis during brain development.
Colonic PDGFRα Overexpression Accompanied Forkhead Transcription Factor FOXO3 Up-Regulation in STZ-Induced Diabetic Mice.
Transcriptome analysis of PDGFRα+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFRα+ cell hyperplasia.
ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers.
Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination.
Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries.
Physiologically activated mammary fibroblasts promote postpartum mammary cancer.
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.
Leptin sustains spontaneous remyelination in the adult central nervous system.
Real-time and non-invasive monitoring of embryonic stem cell survival during the development of embryoid bodies with smart nanosensor.
USP9X deletion elevates the density of oligodendrocytes within the postnatal dentate gyrus.
Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model.
Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation.
Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development.
AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to β-adrenergic signalling.
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos.
Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development.
Double minute amplification of mutant PDGF receptor α in a mouse glioma model.
Transplanted bone marrow-derived circulating PDGFRα+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
Hypoxia inducible factor-2α regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors.
Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.
Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling.
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation.
Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model.
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.
Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis.
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.
Oligodendroglial metabotropic glutamate receptors are developmentally regulated and involved in the prevention of apoptosis.
Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma.
Grund A, Szaroszyk M, Korf-Klingebiel M, Malek Mohammadi M, Trogisch FA, Schrameck U, Gigina A, Tiedje C, Gaestel M, Kraft T, Hegermann J, Batkai S, Thum T, Perrot A, Remedios CD, Riechert E, Völkers M, Doroudgar S, Jungmann A, Bauer R, Yin X, Mayr M, Wollert KC, Pich A, Xiao H, Katus HA, Bauersachs J, Müller OJ, Heineke J
EMBO molecular medicine 2019 Oct;11(10):e10018
EMBO molecular medicine 2019 Oct;11(10):e10018
Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle.
Wosczyna MN, Konishi CT, Perez Carbajal EE, Wang TT, Walsh RA, Gan Q, Wagner MW, Rando TA
Cell reports 2019 May 14;27(7):2029-2035.e5
Cell reports 2019 May 14;27(7):2029-2035.e5
Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
Lukjanenko L, Karaz S, Stuelsatz P, Gurriaran-Rodriguez U, Michaud J, Dammone G, Sizzano F, Mashinchian O, Ancel S, Migliavacca E, Liot S, Jacot G, Metairon S, Raymond F, Descombes P, Palini A, Chazaud B, Rudnicki MA, Bentzinger CF, Feige JN
Cell stem cell 2019 Mar 7;24(3):433-446.e7
Cell stem cell 2019 Mar 7;24(3):433-446.e7
Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration.
Han X, Wang Y, Pu W, Huang X, Qiu L, Li Y, Yu W, Zhao H, Liu X, He L, Zhang L, Ji Y, Lu J, Lui KO, Zhou B
Stem cell reports 2019 Mar 5;12(3):624-638
Stem cell reports 2019 Mar 5;12(3):624-638
Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice.
Zhang X, Wang X, Yin H, Zhang L, Feng A, Zhang QX, Lin Y, Bao B, Hernandez LL, Shi GP, Liu J
Cell reports 2019 Jul 16;28(3):792-803.e4
Cell reports 2019 Jul 16;28(3):792-803.e4
Heterozygosity for Nuclear Factor One X in mice models features of Malan syndrome.
Oishi S, Harkins D, Kurniawan ND, Kasherman M, Harris L, Zalucki O, Gronostajski RM, Burne THJ, Piper M
EBioMedicine 2019 Jan;39:388-400
EBioMedicine 2019 Jan;39:388-400
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage.
Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M
Nature immunology 2019 Feb;20(2):163-172
Nature immunology 2019 Feb;20(2):163-172
Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds.
Guerrero-Juarez CF, Dedhia PH, Jin S, Ruiz-Vega R, Ma D, Liu Y, Yamaga K, Shestova O, Gay DL, Yang Z, Kessenbrock K, Nie Q, Pear WS, Cotsarelis G, Plikus MV
Nature communications 2019 Feb 8;10(1):650
Nature communications 2019 Feb 8;10(1):650
Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration.
Carr MJ, Toma JS, Johnston APW, Steadman PE, Yuzwa SA, Mahmud N, Frankland PW, Kaplan DR, Miller FD
Cell stem cell 2019 Feb 7;24(2):240-256.e9
Cell stem cell 2019 Feb 7;24(2):240-256.e9
TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung.
Wojahn I, Lüdtke TH, Christoffels VM, Trowe MO, Kispert A
Respiratory research 2019 Dec 23;20(1):292
Respiratory research 2019 Dec 23;20(1):292
In Situ Modification of Tissue Stem and Progenitor Cell Genomes.
Goldstein JM, Tabebordbar M, Zhu K, Wang LD, Messemer KA, Peacker B, Ashrafi Kakhki S, Gonzalez-Celeiro M, Shwartz Y, Cheng JKW, Xiao R, Barungi T, Albright C, Hsu YC, Vandenberghe LH, Wagers AJ
Cell reports 2019 Apr 23;27(4):1254-1264.e7
Cell reports 2019 Apr 23;27(4):1254-1264.e7
Myelin repair stimulated by CNS-selective thyroid hormone action.
Hartley MD, Banerji T, Tagge IJ, Kirkemo LL, Chaudhary P, Calkins E, Galipeau D, Shokat MD, DeBell MJ, Van Leuven S, Miller H, Marracci G, Pocius E, Banerji T, Ferrara SJ, Meinig JM, Emery B, Bourdette D, Scanlan TS
JCI insight 2019 Apr 18;4(8)
JCI insight 2019 Apr 18;4(8)
PDGFRα(+) stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.
Joshi PA, Waterhouse PD, Kasaian K, Fang H, Gulyaeva O, Sul HS, Boutros PC, Khokha R
Nature communications 2019 Apr 15;10(1):1760
Nature communications 2019 Apr 15;10(1):1760
Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α.
Jensen SK, Michaels NJ, Ilyntskyy S, Keough MB, Kovalchuk O, Yong VW
Cell reports 2018 Sep 18;24(12):3167-3179
Cell reports 2018 Sep 18;24(12):3167-3179
AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.
Juban G, Saclier M, Yacoub-Youssef H, Kernou A, Arnold L, Boisson C, Ben Larbi S, Magnan M, Cuvellier S, Théret M, Petrof BJ, Desguerre I, Gondin J, Mounier R, Chazaud B
Cell reports 2018 Nov 20;25(8):2163-2176.e6
Cell reports 2018 Nov 20;25(8):2163-2176.e6
Pulmonary pericytes regulate lung morphogenesis.
Kato K, Diéguez-Hurtado R, Park DY, Hong SP, Kato-Azuma S, Adams S, Stehling M, Trappmann B, Wrana JL, Koh GY, Adams RH
Nature communications 2018 Jun 22;9(1):2448
Nature communications 2018 Jun 22;9(1):2448
Perfect chronic skeletal muscle regeneration in adult spiny mice, Acomys cahirinus.
Maden M, Brant JO, Rubiano A, Sandoval AGW, Simmons C, Mitchell R, Collin-Hooper H, Jacobson J, Omairi S, Patel K
Scientific reports 2018 Jun 11;8(1):8920
Scientific reports 2018 Jun 11;8(1):8920
Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice.
Kim SN, Akindehin S, Kwon HJ, Son YH, Saha A, Jung YS, Seong JK, Lim KM, Sung JH, Maddipati KR, Lee YH
Scientific reports 2018 Jun 11;8(1):8856
Scientific reports 2018 Jun 11;8(1):8856
Role of P2X4 Receptor in Mouse Voiding Function.
Yu W, Hill WG, Robson SC, Zeidel ML
Scientific reports 2018 Jan 30;8(1):1838
Scientific reports 2018 Jan 30;8(1):1838
Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner.
Mitew S, Gobius I, Fenlon LR, McDougall SJ, Hawkes D, Xing YL, Bujalka H, Gundlach AL, Richards LJ, Kilpatrick TJ, Merson TD, Emery B
Nature communications 2018 Jan 22;9(1):306
Nature communications 2018 Jan 22;9(1):306
Profiling proliferative cells and their progeny in damaged murine hearts.
Kretzschmar K, Post Y, Bannier-Hélaouët M, Mattiotti A, Drost J, Basak O, Li VSW, van den Born M, Gunst QD, Versteeg D, Kooijman L, van der Elst S, van Es JH, van Rooij E, van den Hoff MJB, Clevers H
Proceedings of the National Academy of Sciences of the United States of America 2018 Dec 26;115(52):E12245-E12254
Proceedings of the National Academy of Sciences of the United States of America 2018 Dec 26;115(52):E12245-E12254
Myelination of the developing lateral olfactory tract and anterior commissure.
Collins LN, Hill DL, Brunjes PC
The Journal of comparative neurology 2018 Aug 1;526(11):1843-1858
The Journal of comparative neurology 2018 Aug 1;526(11):1843-1858
Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion.
Begolly S, Olschowka JA, Love T, Williams JP, O'Banion MK
Glia 2018 Apr;66(4):846-861
Glia 2018 Apr;66(4):846-861
B-1a lymphocytes promote oligodendrogenesis during brain development.
Tanabe S, Yamashita T
Nature neuroscience 2018 Apr;21(4):506-516
Nature neuroscience 2018 Apr;21(4):506-516
Colonic PDGFRα Overexpression Accompanied Forkhead Transcription Factor FOXO3 Up-Regulation in STZ-Induced Diabetic Mice.
Lu H, Zhang C, Song N, Lu C, Tong L, Huang X, Kim YC, Chen J, Xu W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(1):158-171
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(1):158-171
Transcriptome analysis of PDGFRα+ cells identifies T-type Ca2+ channel CACNA1G as a new pathological marker for PDGFRα+ cell hyperplasia.
Ha SE, Lee MY, Kurahashi M, Wei L, Jorgensen BG, Park C, Park PJ, Redelman D, Sasse KC, Becker LS, Sanders KM, Ro S
PloS one 2017;12(8):e0182265
PloS one 2017;12(8):e0182265
ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers.
Gonzalez D, Contreras O, Rebolledo DL, Espinoza JP, van Zundert B, Brandan E
PloS one 2017;12(5):e0177649
PloS one 2017;12(5):e0177649
Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination.
Chen Y, Zhen W, Guo T, Zhao Y, Liu A, Rubio JP, Krull D, Richardson JC, Lu H, Wang R
PloS one 2017;12(12):e0189380
PloS one 2017;12(12):e0189380
Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries.
Aghajanian H, Cho YK, Rizer NW, Wang Q, Li L, Degenhardt K, Jain R
Disease models & mechanisms 2017 Sep 1;10(9):1101-1108
Disease models & mechanisms 2017 Sep 1;10(9):1101-1108
Physiologically activated mammary fibroblasts promote postpartum mammary cancer.
Guo Q, Minnier J, Burchard J, Chiotti K, Spellman P, Schedin P
JCI insight 2017 Mar 23;2(6):e89206
JCI insight 2017 Mar 23;2(6):e89206
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.
Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton ND, Rockenstein E, Masliah E, Peterson KL, Stallcup WB, Chen J, Evans SM
Cell stem cell 2017 Mar 2;20(3):345-359.e5
Cell stem cell 2017 Mar 2;20(3):345-359.e5
Leptin sustains spontaneous remyelination in the adult central nervous system.
Matoba K, Muramatsu R, Yamashita T
Scientific reports 2017 Jan 16;7:40397
Scientific reports 2017 Jan 16;7:40397
Real-time and non-invasive monitoring of embryonic stem cell survival during the development of embryoid bodies with smart nanosensor.
Fu J, Wiraja C, Chong R, Xu C, Wang DA
Acta biomaterialia 2017 Feb;49:358-367
Acta biomaterialia 2017 Feb;49:358-367
USP9X deletion elevates the density of oligodendrocytes within the postnatal dentate gyrus.
Oishi S, Zalucki O, Premarathne S, Wood SA, Piper M
Neurogenesis (Austin, Tex.) 2016;3(1):e1235524
Neurogenesis (Austin, Tex.) 2016;3(1):e1235524
Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model.
Tagge I, O'Connor A, Chaudhary P, Pollaro J, Berlow Y, Chalupsky M, Bourdette D, Woltjer R, Johnson M, Rooney W
PloS one 2016;11(4):e0152480
PloS one 2016;11(4):e0152480
Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation.
Frank DB, Peng T, Zepp JA, Snitow M, Vincent TL, Penkala IJ, Cui Z, Herriges MJ, Morley MP, Zhou S, Lu MM, Morrisey EE
Cell reports 2016 Nov 22;17(9):2312-2325
Cell reports 2016 Nov 22;17(9):2312-2325
Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development.
Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y
Proceedings of the National Academy of Sciences of the United States of America 2016 May 10;113(19):E2589-97
Proceedings of the National Academy of Sciences of the United States of America 2016 May 10;113(19):E2589-97
AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to β-adrenergic signalling.
Shin JH, Lee SH, Kim YN, Kim IY, Kim YJ, Kyeong DS, Lim HJ, Cho SY, Choi J, Wi YJ, Choi JH, Yoon YS, Bae YS, Seong JK
Scientific reports 2016 Mar 18;6:23426
Scientific reports 2016 Mar 18;6:23426
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos.
Lin J, Khan M, Zapiec B, Mombaerts P
Scientific reports 2016 Dec 19;6:39457
Scientific reports 2016 Dec 19;6:39457
Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development.
Daquinag AC, Tseng C, Salameh A, Zhang Y, Amaya-Manzanares F, Dadbin A, Florez F, Xu Y, Tong Q, Kolonin MG
Cell death and differentiation 2015 Feb;22(2):351-63
Cell death and differentiation 2015 Feb;22(2):351-63
Double minute amplification of mutant PDGF receptor α in a mouse glioma model.
Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova NM, Jahanshahi M, Olson LE, Soriano P, Friedel RH
Scientific reports 2015 Feb 16;5:8468
Scientific reports 2015 Feb 16;5:8468
Transplanted bone marrow-derived circulating PDGFRα+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
Iinuma S, Aikawa E, Tamai K, Fujita R, Kikuchi Y, Chino T, Kikuta J, McGrath JA, Uitto J, Ishii M, Iizuka H, Kaneda Y
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 15;194(4):1996-2003
Journal of immunology (Baltimore, Md. : 1950) 2015 Feb 15;194(4):1996-2003
Hypoxia inducible factor-2α regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors.
Duan LJ, Takeda K, Fong GH
PloS one 2014;9(1):e84736
PloS one 2014;9(1):e84736
Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.
Ettle B, Reiprich S, Deusser J, Schlachetzki JC, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J
Molecular and cellular neurosciences 2014 Sep;62:68-78
Molecular and cellular neurosciences 2014 Sep;62:68-78
Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling.
Pinto MP, Dye WW, Jacobsen BM, Horwitz KB
BMC cancer 2014 Oct 1;14:735
BMC cancer 2014 Oct 1;14:735
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
Gibson EM, Purger D, Mount CW, Goldstein AK, Lin GL, Wood LS, Inema I, Miller SE, Bieri G, Zuchero JB, Barres BA, Woo PJ, Vogel H, Monje M
Science (New York, N.Y.) 2014 May 2;344(6183):1252304
Science (New York, N.Y.) 2014 May 2;344(6183):1252304
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
Moore-Morris T, Guimarães-Camboa N, Banerjee I, Zambon AC, Kisseleva T, Velayoudon A, Stallcup WB, Gu Y, Dalton ND, Cedenilla M, Gomez-Amaro R, Zhou B, Brenner DA, Peterson KL, Chen J, Evans SM
The Journal of clinical investigation 2014 Jul;124(7):2921-34
The Journal of clinical investigation 2014 Jul;124(7):2921-34
Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
Fan J, Ponferrada VG, Sato T, Vemaraju S, Fruttiger M, Gerhardt H, Ferrara N, Lang RA
Development (Cambridge, England) 2014 Jan;141(2):448-59
Development (Cambridge, England) 2014 Jan;141(2):448-59
Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation.
Cordani N, Pisa V, Pozzi L, Sciorati C, Clementi E
Stem cells (Dayton, Ohio) 2014 Apr;32(4):874-85
Stem cells (Dayton, Ohio) 2014 Apr;32(4):874-85
Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM
Nature 2013 Dec 12;504(7479):277-281
Nature 2013 Dec 12;504(7479):277-281
Abnormal development of NG2+PDGFR-α+ neural progenitor cells leads to neonatal hydrocephalus in a ciliopathy mouse model.
Carter CS, Vogel TW, Zhang Q, Seo S, Swiderski RE, Moninger TO, Cassell MD, Thedens DR, Keppler-Noreuil KM, Nopoulos P, Nishimura DY, Searby CC, Bugge K, Sheffield VC
Nature medicine 2012 Dec;18(12):1797-804
Nature medicine 2012 Dec;18(12):1797-804
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.
Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang SZ, Ding H, Fariss RN, Becker KG, Lennartsson J, Nagai N, Cao Y, Li X
The Journal of experimental medicine 2010 Apr 12;207(4):867-80
The Journal of experimental medicine 2010 Apr 12;207(4):867-80
Stem cell based delivery of IFN-beta reduces relapses in experimental autoimmune encephalomyelitis.
Makar TK, Trisler D, Bever CT, Goolsby JE, Sura KT, Balasubramanian S, Sultana S, Patel N, Ford D, Singh IS, Gupta A, Valenzuela RM, Dhib-Jalbut S
Journal of neuroimmunology 2008 May 30;196(1-2):67-81
Journal of neuroimmunology 2008 May 30;196(1-2):67-81
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.
Su EJ, Fredriksson L, Geyer M, Folestad E, Cale J, Andrae J, Gao Y, Pietras K, Mann K, Yepes M, Strickland DK, Betsholtz C, Eriksson U, Lawrence DA
Nature medicine 2008 Jul;14(7):731-7
Nature medicine 2008 Jul;14(7):731-7
Oligodendroglial metabotropic glutamate receptors are developmentally regulated and involved in the prevention of apoptosis.
Luyt K, Váradi A, Durant CF, Molnár E
Journal of neurochemistry 2006 Oct;99(2):641-56
Journal of neurochemistry 2006 Oct;99(2):641-56
Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma.
Tejada ML, Yu L, Dong J, Jung K, Meng G, Peale FV, Frantz GD, Hall L, Liang X, Gerber HP, Ferrara N
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 May 1;12(9):2676-88
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 May 1;12(9):2676-88
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
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- Detection of Mouse PDGF Ra by Western Blot. Detection of Mouse PDGF Ra by Western Blot.
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