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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB3372 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3372, RRID:AB_1578535
- Product name
- PDGFRA polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PDGFRA.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.
PDGFRA activating mutations in gastrointestinal stromal tumors.
Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells.
Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J, Kutok J, Clark J, Galinsky I, Griffin JD, Cross NC, Tefferi A, Malone J, Alam R, Schrier SL, Schmid J, Rose M, Vandenberghe P, Verhoef G, Boogaerts M, Wlodarska I, Kantarjian H, Marynen P, Coutre SE, Stone R, Gilliland DG
The New England journal of medicine 2003 Mar 27;348(13):1201-14
The New England journal of medicine 2003 Mar 27;348(13):1201-14
PDGFRA activating mutations in gastrointestinal stromal tumors.
Heinrich MC, Corless CL, Duensing A, McGreevey L, Chen CJ, Joseph N, Singer S, Griffith DJ, Haley A, Town A, Demetri GD, Fletcher CD, Fletcher JA
Science (New York, N.Y.) 2003 Jan 31;299(5607):708-10
Science (New York, N.Y.) 2003 Jan 31;299(5607):708-10
Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells.
Andrae J, Molander C, Smits A, Funa K, Nistér M
Biochemical and biophysical research communications 2002 Aug 23;296(3):604-11
Biochemical and biophysical research communications 2002 Aug 23;296(3):604-11
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of mouse lung tissue lysate (35 ug/lane) with PDGFRA polyclonal antibody (Cat # PAB3372).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PDGFRA polyclonal antibody (Cat # PAB3372) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
