Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- PP-H0723-00 - Provider product page
- Provider
- R&D Systems
- Product name
- Human PPAR alpha/NR1C1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. This antibody specifically recognizes human PPAR alpha and cross-reacts with mouse PPAR alpha . This antibody does not cross-react with human PPAR gamma or PPAR delta . Not yet tested in other species.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- H0723
- Vial size
- 100 ug
- Storage
- This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Submitted references APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production.
Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells.
MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation.
PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells.
Wang FW, Cao CH, Han K, Zhao YX, Cai MY, Xiang ZC, Zhang JX, Chen JW, Zhong LP, Huang Y, Zhou SF, Jin XH, Guan XY, Xu RH, Xie D
The Journal of clinical investigation 2019 Feb 1;129(2):727-743
The Journal of clinical investigation 2019 Feb 1;129(2):727-743
Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells.
Lien SC, Wei SY, Chang SF, Chang MD, Chang JY, Chiu JJ
Cellular signalling 2013 May;25(5):1252-63
Cellular signalling 2013 May;25(5):1252-63
MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation.
Zhou J, Wang KC, Wu W, Subramaniam S, Shyy JY, Chiu JJ, Li JY, Chien S
Proceedings of the National Academy of Sciences of the United States of America 2011 Jun 21;108(25):10355-60
Proceedings of the National Academy of Sciences of the United States of America 2011 Jun 21;108(25):10355-60
PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells.
Huang W, Rha GB, Han MJ, Eum SY, András IE, Zhong Y, Hennig B, Toborek M
Journal of neurochemistry 2008 Oct;107(2):497-509
Journal of neurochemistry 2008 Oct;107(2):497-509
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