BS8105

antibody from Bioworld Technology, Inc

Targeting: GALT

Immunohistochemistry

Antibody data

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Validation data

Product number: BS8105 - Provider product page
Provider: Bioworld Technology, Inc
Product name: GALT polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human GALT.
Description: GALT (galactose-1-phosphate uridylyltransferase) is a 379 amino acid member of the galactose-1-phosphate uridylyltransferase type 1 family of proteins. GALT exists as a homodimer and is believed to play a role in galactose metabolism. More specifically, GALT is responsible for catalyzing the reaction of UDP-glucose with Ï«-D-galactose 1-phosphate to produce Ï«-D-glucose 1-phosphate and UDP-galactose. This is the second step of the Leloir pathway of galactose metabolism. The products of this reaction will either enter the glycolytic pathway to yield energy (Ï«-D-glucose 1-phosphate) or be used as a galactosyl donor in the synthesis of glycoproteins and glycolipids (UDP-galactose). Mutations in the gene encoding GALT can lead to galactosemia, a disorder (occurring from the inability to metabolize galactose) that is characterized by cataracts, mental retardation and jaundice. In newborns, galactosemia can be fatal if lactose is not removed from the diet.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

GALT protein structure - BS8105 shown in red.