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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
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- Product number
- TA504858 - Provider product page
- Provider
- OriGene
- Proper citation
- OriGene Cat#TA504858, RRID:AB_2622653
- Product name
- AFG3L2 mouse monoclonal antibody, clone OTI4B6 (formerly 4B6)
- Antibody type
- Monoclonal
- Description
- AFG3L2 mouse monoclonal antibody, clone OTI4B6 (formerly 4B6)
- Host
- Mouse
- Conjugate
- Unconjugated
- Epitope
- AFG3L2
- Isotype
- IgG
- Antibody clone number
- OTI4B6
- Vial size
- 100 µl
- Concentration
- 1 mg/ml
Submitted references Pathogenic variants in the AFG3L2 proteolytic domain cause SCA28 through haploinsufficiency and proteostatic stress-driven OMA1 activation.
Tulli S, Del Bondio A, Baderna V, Mazza D, Codazzi F, Pierson TM, Ambrosi A, Nolte D, Goizet C, Toro C, Baets J, Deconinck T, DeJonghe P, Mandich P, Casari G, Maltecca F
Journal of medical genetics 2019 Aug;56(8):499-511
Journal of medical genetics 2019 Aug;56(8):499-511
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Supportive validation
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AFG3L2 (RC209058, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AFG3L2.
- Validation comment
- WB
