FNab09765

antibody from FineTest Biotech
Targeting: ZYX
Provider product page for FNab09765
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab09765 - Provider product page
Provider
FineTest Biotech
Product name
Zyxin antibody
Antibody type
Monoclonal
Antigen
Recombinant protein fragment
Description
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin(ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
zyxin
Epitope
IgG1
Isotype
IgG
Antibody clone number
8D5
Vial size
100¦Ìg
Concentration
Protein A+G purification
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
ZYX protein structure - FNab09765 shown in red.