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- Product number
- ABIN395405 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Zyxin (ZYX) (AA 1-573) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-573
- Isotype
- IgG
- Antibody clone number
- 2C10-4A7
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Synemin interacts with the LIM domain protein zyxin and is essential for cell adhesion and migration.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Zyxin is involved in thrombin signaling via interaction with PAR-1 receptor.
Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators.
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
Synemin interacts with the LIM domain protein zyxin and is essential for cell adhesion and migration.
Sun N, Huiatt TW, Paulin D, Li Z, Robson RM
Experimental cell research 2010 Feb 1;316(3):491-505
Experimental cell research 2010 Feb 1;316(3):491-505
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators., NORDIL investigators., BRIGHT Consortium.
American journal of human genetics 2009 Nov;85(5):628-42
American journal of human genetics 2009 Nov;85(5):628-42
Zyxin is involved in thrombin signaling via interaction with PAR-1 receptor.
Han J, Liu G, Profirovic J, Niu J, Voyno-Yasenetskaya T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 Dec;23(12):4193-206
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 Dec;23(12):4193-206
Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner.
Hirata H, Tatsumi H, Sokabe M
Journal of cell science 2008 Sep 1;121(Pt 17):2795-804
Journal of cell science 2008 Sep 1;121(Pt 17):2795-804
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