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LearnBAF2447
antibody from R&D Systems
Targeting: IGF2R
CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI
Western blot
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- BAF2447 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IGF-II R/IGF2R Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IGF-II R/IGF2R in ELISAs and Western blots. In sandwich ELISAs, less than 0.2% cross-reactivity with recombinant human (rh) IGF-I R, rhIGF-I, and rhIGF-II is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
P11717- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references CD44+ fibroblasts increases breast cancer cell survival and drug resistance via IGF2BP3-CD44-IGF2 signalling.
Liu Y, Yu C, Wu Y, Sun X, Su Q, You C, Xin H
Journal of cellular and molecular medicine 2017 Sep;21(9):1979-1988
Journal of cellular and molecular medicine 2017 Sep;21(9):1979-1988
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of IGF-II R/IGF2R in Human Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Human IGF-II R/IGF2R Biotinylated Antigen Affinity-purified Polyclonal Antibody (Catalog # BAF2447, filled histogram) or control antibody (Catalog # BAF108, open histogram), followed by Streptavidin-Phycoerythrin (Catalog # F0040).
