HPA003310

antibody from Atlas Antibodies

Targeting: TTC8 BBS8, RP51

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA003310

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA003310, RRID:AB_1080413

Product name

Anti-TTC8

Antibody type

Polyclonal

Description

Affinity purified using the PrEST antigen as affinity ligand

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

TQMLEKSPYDQAAWILKARALTEMVYIDEIDVDQE
GIAEMMLDENAIAQVPRPGTSLKLPGTNQTGGPSQ
AVRPITQAGRPITGFLRPSTQSGRPGTMEQAI


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors.

Xu Q, Zhang Y, Wei Q, Huang Y, Li Y, Ling K, Hu J
Scientific reports 2015 Jul 7;5:11855

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Essential role of the chaperonin CCT in rod outer segment biogenesis.

Sinha S, Belcastro M, Datta P, Seo S, Sokolov M
Investigative ophthalmology & visual science 2014 May 22;55(6):3775-85

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BBS mutations modify phenotypic expression of CEP290-related ciliopathies.

Zhang Y, Seo S, Bhattarai S, Bugge K, Searby CC, Zhang Q, Drack AV, Stone EM, Sheffield VC
Human molecular genetics 2014 Jan 1;23(1):40-51

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The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome

Chamling X, Seo S, Searby C, Kim G, Slusarski D, Sheffield V, Dutcher S
PLoS Genetics 2014 February;10(2)

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in a subset of cells in red pulp.